Habibe DURMUŞOĞLU, ÖZGE TUĞÇE PAŞAOĞLU, Bayram ŞENLİK, NURAY BOZKURT, BÜLENT ÇELİK, HATİCE PAŞAOĞLU

Gebelik Komplikasyonlarında Serum Çinko, Bakır ve Serüloplazminin Önemi

Amaç: Çalışmamızda gebelik komplikasyonlarından preeklampsi ve missed abortusta serum çinko ve bakır seviyeleri ile serüloplazmin oksidaz aktivitesi incelendi. Gereç ve Yöntem: Bu amaçla gebelik komplikasyonlarından sık görülen preeklampsi (n =10) ve missed abortus tanılı hastaların (n=20) serum çinko, bakır, serüloplazmin değerleri, aynı haftalardaki sağlıklı gebelerle (sırasıyla n =10, n =20), karşılaştırıldı. Serum çinko ve bakır düzeyleri atomik absorpsiyon spektrofotometre yöntemi ile ölçüldü. Serüloplazmin oksidaz aktivitesi ise spektrofotometrik olarak belirlendi. Bulgular: Preeklampsi grubunda çinko düzeyinde kontrollere göre düşme görüldü, ancak istatistik anlamlı bir fark gözlenmedi. Serum bakır düzeyi ve serüloplazmin oksidaz aktivitesinde artış olduğu tespit edildi (p

The Significance of Serum Zinc, Copper and Ceruloplasmin in Pregnancy Complications

Objective: In our study, serum zinc and copper levels, and ceruloplasmin oxidase activity were investigated in two of the pregnancy complications; preeclampsia and missed abortion. Material and Method: For this purpose, serum zinc, copper and ceruloplasmin oxidase activity levels of the patients diagnosed with frequently seen pregnancy complications preeclampsia (n =10) and missed abortion (n =20) were compared with healthy pregnant women (n =10 and n =20, respecti-vely) of corresponding weeks. Serum zinc and copper levels were measured using atomic absorption spectroscopy. Ceruloplasmin oxidase activity was determined spectrophotometrically. Results: In the preeclampsia group, zinc levels were found to be diminished compared with controls, however this difference was not statistically significant. Serum copper and ceruloplasmin oxidase activity were detected to be increased (p

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