Yetişkin bir hastada akut lenfoblastik löseminin pankreas tutulumu: Bir Olgu Sunumu

Akut lenfoblastik lösemi, çocukluk çağı lösemisinin%80'inden sorumludur ve tüm yetişkin lösemilerin %20'sini oluşturur. Granülositik sarkom, immatür miyeloid seri hücrelerden kaynaklanan ekstramedüller bir tümördür ve akut lösemi hastalarının%2.5-9.1'inde görülür. Genellikle kemik ve yumuşak dokunun subperiostal bölgesinde görülmekle birlikte vücudun her yerinde tespit edilebilir. Granülositik sarkom hem pediyatrik hem de yetişkin hastaları etkilese de (3 ay ile 89 yaş arasında vakalar bildirilmiştir) pediatrik hastalarda sıklıkla teşhis edilir. Granülositik sarkomun ana tedavisi sitoredüksiyon ve remisyon sağlamak için kemoterapidir. Kemoterapi, remisyon indüksiyonu, merkezi sinir sistemi profilaksisi ve remisyon sonrası tedaviden oluşur. Radyoterapi semptomatik granülositik sarkom, omurilik kompresyonu, vena kava superior sendromu ve mediastinal kitleye bağlı solunum yolu kompresyonunda kullanılır.

Anahtar Kelimeler:

Akut lenfoblastik lösemi, Granülositik sarkom, Radyoterapi, Acute lymphoblastic leukemia, Granulocytic sarcoma, Radiotherapy

Pancreatic involvement of acute lymphoblastic leukemia in an adult patient: A Case Report

In acute lymphoblastic leukemia, it is responsible for 80% of childhood leukemia and accounts for 20% of all adult leukemias. Granulocytic sarcoma is an extramedullary tumor arising from immature myeloid serial cells and is seen in 2.5-9.1% of acute leukemia patients. Although it is generally seen in the subperiostal region of bone and soft tissue, it can be detected in all parts of the body. The main treatment of granulocytic sarcoma is chemotherapy to achieve cytoreduction and remission. Chemotherapy consists of remission induction, central nervous system prophylaxis, and post-remission treatment. Radiotherapy is used in symptomatic granulocytic sarcoma, spinal cord compression, vena cava superior syndrome and respiratory tract compression due to mediastinal mass.

Keywords:

Acute lymphoblastic leukemia, Granulocytic sarcoma, Radiotherapy,

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