SUMMARYIn this article, a neview of the literature about pyogenic granuloma has been made and a very interesting case report established.Patient N.C,a 25-year-old man was admitted to the Periodontology Department in Istanbul Dentat Faculty with a pyogenic granuloma growing on the gingiva around the upper labial frenum.Under this granuloma, a very deep cavity, exposing the pulp tissue, on the cementum of an upper right central incisor was observed when it was removed by surgically.A search of the literature has failed to reveal and or suggest that dental caries are not responsible of being one of the etiologic factors in this pathologic condition.But with this case, we can state that caries may be an etiological factor of pyogenic granuloma.