Fatih ASUTAY, Ahmet ACAR, Ümit YOLCU, Mustafa KIRTAY, Hilal ALAN

Dental kök hücre kaynakları ve kemik doku mühendisliğinde kullanılma potansiyelleri

Doku mühendisliği yaklaşımları, kemik iyileşmesi ile ilgilenen her tıp alanında heyecan uyandırmaktadır. İyileşme sürelerinin kısalması, daha kaliteli ve fonksiyonel doku elde edilmesi ve ikincil bir cerrahi sahaya gereksinimi ortadan kaldırması bu yaklaşımların nihai hedeflerindendir. Mezenşimal kök hücreler bu alandaki çalışmalarda giderek artarak kullanılmakta ve sonuçlar umut vermektedir. Dental kök hücreler de hem kolay temin edilebilmesi hem de üstün özellikleri sebebiyle ön plana çıkmaktadırlar. Bu çalışmada dental kök hücrelerin kemik doku mühendisliği yaklaşımları için önemi ve rejenerasyon potansiyelleri incelenmiştir.

Anahtar Kelimeler:

Dental kök hücreler, kemik dokusu mühendisliği, oral ve maksillofasiyal cerrahi

DENTAL STEM CELL SOURCES AND THEIR POTENTIALS FOR BONE TISSUE ENGINEERING

Tissue engineering arouses excitement in all medical fields that deal with bone healing. The iyileşmesi ile ilgilenen her tıp alanında heyecan ultimate aim of these approaches are to shorten uyandırmaktadır. İyileşme sürelerinin kısalması, daha the healing process, obtain highly differentiated kaliteli ve fonksiyonel doku elde edilmesi ve ikincil functional tissues and eliminate the need for a second bir cerrahi sahaya gereksinimi ortadan kaldırması bu surgical site required for autogenous bone grafts. Mesenchymal stem cells have been increasingly hücreler bu alandaki çalışmalarda giderek artarak used in the experiments which were conducted in kullanılmakta ve sonuçlar umut vermektedir. Dental these fields and the results are promising. Dental stem cells have come to the forefront both because of their relative ease of access and also their Bu çalışmada dental kök hücrelerin kemik doku superior characteristics. This article investigates mühendisliği yaklaşımları için önemi ve rejenerasyon the importance of dental stem cells for bone tissue engineering and their regeneration potentials

Keywords:

Dental stem cells, bone tissue engineering, oral and maxillofacial surgery,

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