Baseline Hemoglobin Levels Predict AllCause Mortality After Saphenous Vein Graft Interventions

Baseline Hemoglobin Levels Predict AllCause Mortality After Saphenous Vein Graft Interventions

Objective: Reduced baseline hemoglobin level is associated with worse outcomes in many cardiovascular conditions including percutaneous interventions of native coronary arteries. However, this relationship has not been studied in saphenous vein graft disease undergoing elective percutaneous intervention. Metods: In this study, we evaluated baseline hemoglobin levels of 105 patients undergoing saphenous vein graft intervention. The mean follow-up was 42.4±18.4 months, and the end-point of our study was all-cause mortality. Results: Twelve patients suffered all-cause mortality, and these patients’ mean baseline hemoglobin levels were 2 g/dl lower (11.7±1.0 vs. 13.7±1.5, p=0.005), and their ejection fractions were 22% lower (49.3±10,8 vs. 38.3±12,4, p=0.014) than those of the patients without all-cause mortality. A hemoglobin cut-off 12.55 g/dL discriminated all-cause mortality with an accuracy of 85% (sensitivity: 83,3%, specificity: 76.4%, p=

___

  • Brilakis  ES,  O’Donnell  CI,  Penny  W,  et al. Percutaneous coronary intervention in native coronary arteries versus bypass grafts in patients with prior coronary artery bypass graft surgery: insights from the veterans affairs clinical assessment, reporting, and tracking program. JACC Cardiovasc Interv. 2016;9:884–893.
  • Guedeney P, Sorrentino S,  Claessen B,  Mehran R. The link between anemia and adverse outcomes in patients with acute coronary syndrome. Expert Review of Cardiovascular Therapy. Volume 17, Issue 3, 4 March 2019, Pages 151-159
  • Sulaiman K, Prashanth P, Al-Zakwani I, et al. Impact of anemia on in-hospital, one-month and one-year mortality in patients with acute coronary syndrome from the Middle East. Clin Med Res. 2012;10:65–71.
  • Wang X, Qiu M, Qi J, et al. Impact of anemia on long-term ischemic events and bleeding events in patients undergoing percutaneous coronary intervention: a system review and meta-analysis. J Thorac Dis. 2015;7:2041–2052.
  • Yazji K, Abdul F, Elangovan S, et al. Baseline anemia in patients undergoing percutaneous coronary intervention after an acute coronary syndrome-A paradox of high bleeding risk, high ischemic risk, and complex coronary disease. J Interv Cardiol. 2017;30:491–499.
  • Poludasu S, Marmur JD, Weedon J, et al. Effect of hemoglobin level on long-term all-cause mortality after percutaneous coronary intervention in African-Americans. Am J Cardiol.  2009  Apr 15;103(8):1078-82.
  • Lopes RD, Mehta RH, Hafley GE, for the PREVENT IV Investigators, et al. Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgery. Circulation. 2012;125:749–75.
  • Heuser R,  Moualla SK. Choose your battles wisely! Saphenous vein graft chronic total occlusion interventions, a path less traveled, a frontier to be mostly avoided. Catheter Cardiovasc Interv.  2014 Jun 1;83(7):1033-4.
  • Varghese, I,  Samuel, J,  Banerjee, S,  Brilakis, ES.  Comparison of percutaneous coronary interventions in native coronary arteries vs. bypass grafts in patient with prior coronary artery bypass graft surgery. Cardiovasc Revasc Med 2009;  10: 103– 109.
  • 10. Mehta RH, Honeycutt E, Shaw LK, et al. Clinical correlates of longterm mortality after percutaneous interventions of saphenous vein grafts. Am Heart J. 2006 Oct;152(4):801-6.
  • 11. Sabatine MS, Morrow DA, Giugliano RP, et al. Association of hemoglobin levels with clinical outcomes in acute coronary syndromes. Circulation. 2005 Apr 26;111(16):2042-9.
  • 12. Arant CB, Wessel TR, Olson MB, et al. Hemoglobin level is an independent predictor for adverse cardiovascular outcomes in women undergoing evaluation for chest pain: results from the National Heart, Lung, and Blood Institute Women’s Ischemia Syndrome Evaluation Study.  J Am Coll Cardiol.  2004;  43:  20092014.
  • 13. Brener SJ, Mehran R, Dangas GD, et al. Relation of Baseline Hemoglobin Levels and Adverse Events in Patients With Acute Coronary Syndromes (from the Acute Catheterization and Urgent Intervention Triage strategY and Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction Trials).Am J Cardiol. 2017 Jun 1;119(11):1710-1716.
  • 14. Hosseini SK, Ansari MJ, Lotfi Tokaldany M, et al. Association between preprocedural hemoglobin level and 1-year outcome of elective percutaneous coronary intervention. J Cardiovasc Med (Hagerstown). 2014 Apr;15(4):331-5. 
  • 15. Kitai Y, Ozasa N, Morimoto T, et al. Prognostic implications of anemia with or without chronic kidney disease in patients undergoing elective percutaneous coronary intervention. Int J Cardiol.  2013  Oct 15;168(6):5221-8.
  • 16. Lee PC, Kini AS, Ahsan C, et al. Anemia is an independent predictor of mortality after percutaneous coronary intervention. J Am Coll Cardiol.  2004 Aug 4;44(3):541-6.
  • 17. Stahli B, Gebhard C, Gick M, et al. Impact of anemia on long-term outcomes after percutaneous coronary intervention for chronic total occlusion. Catheter Cardiovasc Interv. 2018;91:226-233.
  • 18. Moo-Young Kim, Sun Ha Jee, Ji Eun Yun, Soo Jin Baek, Duk-Chul Lee. Hemoglobin Concentration and Risk of Cardiovascular Disease in Korean Men and Women - The Korean Heart Study. J Korean Med Sci. 2013 Sep; 28(9): 1316–1322.
  • 19. Nikolsky E, Mehran R, Aymong ED, et al. Impact of anemia on outcomes of patients undergoing percutaneous coronary interventions. Am J Cardiol 2004;94:1023–1027.
  • 20. Tejada JG, Velazquez M, Hernandez F, Albarran A, Gomez I, Rodriguez S,  et al. Percutaneous revascularization in patients with previous coronary artery bypass graft surgery. Immediate and 1-year clinical outcomes. Int J Cardiol. 2009 May 15;134(2):201-6.
European Journal of Therapeutics-Cover
  • ISSN: 2564-7784
  • Başlangıç: 1990
  • Yayıncı: Fatma Taşçı
Sayıdaki Diğer Makaleler

HLA-G with Benefits and Damages: A Review

İbrahim PİRİM, Burcu CERCİ GÜRBÜZ, Mustafa SOYOZ, Tülay KILIÇARSLAN AYNA

Dynamic Thiol/ Disulfide Balance in Children with Acute Malnutrition

Özcan EREL, Mahmut DEMİR

Investigation of Various Virulence Factors and SCCmec Types in the Healthcare-associated and Community-associated Methicillin Resistance Staphylococcus aureus Strains

Selçuk KAYA, Şafak ERMERTCAN, İsmail ÖZTÜRK, Salih Atakan NEMLİ, Süreyya Gül YURTSEVER, Abdurrahman AYGÜL

Evaluation of Corneal Histopathologic Changes in Rabbits Due To Topical Mitomycin C Application in Different Doses and Periods

Şeyda ERDOĞAN, Kemal YAR, Altan A. OZCAN, Yurdun KUYUCU, Sait POLAT

Rare Cause of Cerebellar Mutism in Childhood: Vertebral Artery Dissection

Serdal GÜNGÖR, Bilge ÖZGÖR, Mahmut ASLAN, Serkan KIRIK

The Relationship between Mitral Chordae Rupture and Inflammation Level and Oxidative Stress

Fethi YAVUZ, Yurdaer DÖNMEZ, Murat YÜCE, Özge Özcan ABACIOĞLU, Vedat DAVUTOĞLU, Mehmet KAPLAN

Outcome of Elderly Nasopharyngeal Carcinoma Patients: A Single Center Study

Gözde YAZİCİ, Hamit BAŞARAN, İbrahim GÜLLÜ, Mustafa CENGİZ, Gökhan ÖZYİĞİT, Yurday ÖZDEMİR, Nilda SÜSLÜ

The Relationship Between Cd 74 Levels, Macrophage Migration Inhibitory Factor Gene Polymorphism and Clinical Features in Patients with Ankylosing Spondylitis

Sacide PEHLİVAN, Mazlum Serdar AKALTUN, Ali AYDENİZ, Savas GURSOY, Özlem ALTINDAĞ, Ali GUR, Tekin KARSLIGİL

Baseline Hemoglobin Levels Predict AllCause Mortality After Saphenous Vein Graft Interventions

Erdem DİKER, Savaş ÇELEBİ, Müjgan TEK, Berkten BERKALP, Mehmet ÖZGEYİK, Basri AMASYALI, Mehmet Serkan ÇETİN

Novel Methods for Diagnosis Of Blood-Borne Protozoa

Fahriye EKŞİ, Deniz GAZEL