Onur GÖNÜL, Erkin DOĞAN, Ahmet Usame ÇİÇEK, Emine Tuna AKDOĞAN, İbrahim Murat AFAT

Oral ve Maksillofasiyal Cerrahide Trombosit Konsantrelerinin Kullanımı

Günümüzde yeni teknolojilerin gelişmesiyle diş hekimliği alanında birçok farklı tedavi yöntemi klinik uygulamalar arasına girmektedir. Hastanın otojen kanından elde edilen trombositten zengin konsantrasyon içerikli ajanlar da yara iyileşmesinde kullanılmaya başlanan son dönem yeniliklerinden biridir. Tam kan konsantreleri uygulamalarında günümüzde yapılan çalışmalarla çeşitli tedavi yaklaşımları oluşmuştur. Tıpta birçok alanda faydalanılan bu konsantrelerin kullanımı; diş hekimliğinde de son yıllarda artarak yaygınlaşmaktadır. Araştırmalar daha çok tıp alanında olsa dahi; ağız-diş ve çene cerrahisinde de fazla sayıda çalışma yapılmıştır. İçeriğinde bulunan büyüme faktörleri sayesinde anjiyogenez, osteogenesis, fibroplazi ve hücre proliferasyonu sağlaması; buna bağlı olarak yara iyileşmesi ve rejenerasyonda önemli role sahip olması endodonti ve periodontoloji gibi diş hekimliğinin diğer alanlarında da kullanımını cazip hale getirmektedir. Trombosit konsantrelerinin bu etkisiyle oral cerrahide sinus lifting, kemik augmentasyonları, yumuşak doku uygulamaları, çekim sonrası yara iyileşmeleri gibi birçok uygulamada da olumlu sonuçlar rapor edilmiştir. Bu derlemede oral ve maksillofasiyel cerrahi branşında trombosit konsantrasyonlarının tarihçesini, gelişimini ve uygulamalarını anlatmak amaçlanmaktadır.

Anahtar Kelimeler:

Plateletten zengin fibrin, plateletten zengin plazma, sinus lifting, büyüme faktörleri, rejenerasyon, oral ve maksillofasiyel cerrahi

Use of Platelet Derived Blood Concentrates in Oral and Maxillofacial Surgery

Today, with the development of new technologies in the field of dentistry can benefit from a variety of different methods. Platelet rich concentration agents obtained from the patient's autogenous blood. Various treatment approaches have been formed with the studies conducted today in the applications of whole blood concentrates. Once reported to be effective in wound healing and bone formation, it is widely used in the dentistry. The use of these concentrates, which are used in many fields in medicine, has been increasing in recent years in dentistry. Even if the research is mostly in the field of medicine; a large number of studies have also been conducted in oral and maxillofacial surgery. It provides angiogenesis, osteogenesis, fibroplasia and cell proliferation with the growth factors contained in it; due to this, it has an important role in wound healing and regeneration, which makes it preferable to use in other areas of dentistry such as endodontics and periodontology. Positive results have also been reported in many applications such as sinus lifting, bone augmentations, soft tissue applications, and wound healing after tooth extractions in oral surgery due to this effect of platelet concentrates. In this review, we aim to describe the history, development and applications of platelet concentrations in the oral and maxillofacial surgery branch.

Keywords:

Platelet rich fibrin, platelet rich plasma, sinus lifting, growth factor, regeneration, oral and maxillofacial surgery,

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