Therapeutic Approachs to Breast Phyllodes Tumor

Filloides tümörler memenin oldukça nadir görülen tümörlerindendir. Genellikle hızlı büyüyen kitle şikayeti ile ortaya çıkarlar ve klinik pratikte sıklıkla fibroadenom ile karıştırılırlar. Bu nedenle genellikle cerrahi eksizyon sonrası tanı koyulduğu için meme hastalıkları ile spesifik olarak ilgilenmeyen merkezlerde tedavi yeterliliği ve klinik takip konularında tereddütler oluşabilmektedir. Bu yazıda memenin filoides tümörlerinin tedavi seçeneklerini kısaca gözden geçirdik

Therapeutic Approachs to Breast Phyllodes Tumor

Phyllodes tumors are very rare tumors of the breast. They usually present in fast-growing mass form and are confused with diagnosis of fibroadenoma in daily clinical practice. The adequacy of treatment and follow-up may be hesitated in some centers which are not engaged with breast disease spesifically due to post-surgical excisional diagnosis in usual. In this article, we have reviewed the treatment options of phyllodes tumors of the breast.

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  • Kario K, Maeda S, Mizuno Y, Makino Y, Tankawa H, Kitazawa S. Phyllodes tumor of the breast: a clinicopath- ologic study of 34 cases. J Surg Oncol 1990;45(1):46-51.
  • Muller J. Ueber den feineran Bau unddie Forman der Krankhaften Geschwilste. Berlin: G Reimer, 1838
  • Lee B, Pack G. Giant intracanalicular fibroadenomyxoma of the breast. The so-called cystosarcoma phyllodes mam- mae of Johannes Muller. Am J Can 1931;93(1):250-68.
  • Ben Hassouna J, Damak T, Gamoudi A, et al. Phyllodes tumors of the breast: a case series of 106 patients. Am J Surg 2006;192(2):141-7.
  • Stebbing JF, Nash AG. Diagnosis and management of phyl- lodes tumour of the breast: experience of 33 cases at a specialist centre. Ann R Coll Surg Engl 1995;77(3):181-4.
  • Nielsen VT, Andreasen C. Phyllodes tumor of the male breast. Histopathology 1987;11(7): 761-2.
  • Pietruszka M, Barnes L. Cystosaroma phyllodes: a clinico- pathologic analysis of 42 cases. Cancer 1978;41(5): 1974-83.
  • Kario K, Maeda S, Mizuno Y, Makino Y, Tankawa H, Kitazawa S. Phyllodes tumor of the breast: a clinicopath- ologic study of 34 cases. J Surg Oncol 1990; 45(1):46-51.
  • Gatta G, Iaselli F, Parlato V, Di Grezia G, Grassi R, Rotondo A. Differential diagnosis between fibroadenoma, giant fi- broadenoma and phyllodes tumour: sonographic features and core needle biopsy. Radiol Med 2011;116(6):905-18.
  • Kapiris I, Nasiri N, A’Hern R, Healy V, Gui GP. Outcome and predictive factors of local recurrence and distant metas- tases following primary surgical treatment of high-grade malignant phyllodes tumours of the breast. Eur J Surg Oncol 2001; 27(8):723-30.
  • Roa JC, Tapia O, Carrasco P, et al. Prognostic factors of phyl- lodes tumor of the breast. Pathol Int 2006;56(6):309-14.
  • Reinfuss M, Mitus J, Duda K, Stelmach A, Rys J, Smolak K. The treatment and prognosis of patients with phyllodes tumor of the breast: An analysis of 170 cases. Cancer 1996;77(5): 910-6.
  • Verma S, Singh RK, Rai A, Pandey CP, Singh M, Mohan N. Extend of surgery in the management of phyllodes tumor of the breast: a retrospective multicenter study from India. J Cancer Res Ther 2010;6(4):511-5.
  • Tan PH, Thike AA, Tan WJ, et al. Predicting clinical be- haviour of breast phyllodes tumours: a nomogram based on histological criteria and surgical margins. J Clin Pathol 2012; 65(1):69-76.
  • Guillot E, Couturaud B, Reyal F, et al. Management of phyllodes breast tumors. Breast J 2011;17(2):129-37.
  • Akin M, Irkorucu O, Koksal H, et al. Phyllodes tumor of the breast; a case series. Bratisl Lek Listy 2010;111(5):271-4.
  • Khosravi-Shahi P. Management of non metastatic phyl- lodes tumors of the breast: review of the literature. Surg Oncol 2011;20(4):e143-8.
  • Parker SJ, Harries SA. Phyllodes tumors. Postgrad Med L 2001; 77(909):428-35. 10
  • Cohn-Cedermark G, Rutqvist LE, Rosendahl I, Silfversward C. Prognostic factors in cystosarcoma phyllodes. A clinico- pathologic study of 77 patients. Cancer 1991;68(9):2017-22.
  • Barth RJ, Wells WA, Mitchell SE, Cole BF. A prospective, multi-institutional study of adjuvant radiotherapy after resection of malignant phyllodes tumors. Ann Surg Oncol 2009;16(8):2288-94.
  • Belkacemi Y, Bousquet G, Marsiqlia H, et al. Phyllodes tumor of the breast. Int J Radiat Oncol Biol Phys 2008;70(2):492-500.
  • Reimer T. Management of rare histological types of breast tumors. Breast Care (Basel) 2008;3(3):190-6.
  • McDonald OK, Lee CM, Tward JD, Chappel CD, Gaffney DK. Malignant phyllodes tumor of the female breast: as- sociation of primary therapy with cause-spesific survival from the Surveillance, Epidemiology, and End Results (SEER) program. Cancer 2006;107(9):2127-33.
  • Morales-Vasquez F, Gonzalez-Angulo AM, Broqlio K, et al. Adjuvant chemotherapy with doxorubicin and da- carbazine has no effect in recurrence-free survival of malignant phyllodes tumors of the breast. Breast J 2007;13(6):551-6.