Nicolau Syndrome After Diclofenac-Thiocolchicoside Intramuscular Injection

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Nicolau Syndrome After Diclofenac-Thiocolchicoside Intramuscular Injection

Nicolau syndrome (NS), also known as embolia cutis medicomentosa and livedo-like dermatitis, is a rare complication of an intramuscular injection characterized by severe pain, skin discoloration, and varying levels of tissue necrosis at the site of the injection.
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  • De Sousa R, Dang A, Rataboli P V. Nicolau syndrome fol- lowing benzathine penicillin. J Postgrad Med 2008;54(4): 332-4.
  • Masthan SD, Salome, Madhav, et al. Nicolau syndrome. Indian J Dermatol Venereol Leprol 2002;68:45-6.
  • Kim K K. Nicolau Syndrome in Patient Following Diclofenac Administration: A case Report. Ann Dermatol 2011;23(4):501-3.
  • Erkek E, Tuncez F, Sanli C, et al. Nicolau syndrome in a newborn caused by triple DTP vaccination. J Am Acad Dermatol 2006; 54: 241-2.
  • McKinney C, Sharma N, Jerath RS. Livedoid dermatitis (Nicolau syndrome) following intra-articular glucocorti- coid injection. J Clin Rheumatol 2014 Sep;20(6):339-40
  • Nayci S, Gurel MS. Nicolau syndrome following intra- muscular diclofenac injection. Indian Dermatol Online J 2013;4(2):152-3.
  • Luton K, Garcia C, Poletti E, Koester G. Nicolau Syndrome: Three cases and review. Int J Dermatol 2006;45:1326–8.
  • Figure 1. Necrotic plaque surrounded by a livedoid,
  • reticular erythematous patch on the right buttock.
European Journal of General Medicine-Cover
  • Yayın Aralığı: 4
  • Başlangıç: 2015
  • Yayıncı: Sağlık Bilimleri Araştırmaları Derneği
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