Samaila MODUPEOLA, Modupeola Omotara SAMAİLA

Extra-cutaneous Palatal Malignant Melanoma in Middle -Aged Females

Ağız boşluğunun malign melanoması özellikle yaşlı erkekleri etkileyen nadir görülen bir agresiv tümördür. 21 yıllık ağız boşluğu malign melanomasıdeğerlendirildi. Yaş aralığı 27-80 yıl ve ortalaması ise 49.8 idi. Semptom süresi 2 ay ile bir yıl arasında değişmekte idi. Muayenede lenf nodu genişlemesi olan 7 olguda sert damakta lokalize değişik ölçülerde ülserasyon ve kanama gösterdi. Damak melanomaları hızlı ilerleme ve çoğu hastalar daha kötü prognoz gösterirler. Sınıflandırma ve tedavisi halen deri melanomasına göre yapılmaktadır. Erken dönem hastalık sıklıkla asemptomatiktir. Bundan dolayı klinisyenlerin agresiv tümörün mortalite ve morbiditesini azaltması için bu hastalık hakkında bilgi düzeylerini artırması gerekmektedir

Anahtar Kelimeler:

Melanom, ekstrakutenöz, kadın, damak

Extra-cutaneous Palatal Malignant Melanoma in Middle -Aged Females

Malignant melanoma of the oral cavity is an uncommon aggressive tumour that preferentially affects elderly males. A twenty-one year analysis of oral malignant melanoma cases were evaluated. The age range was 27-80 years with a mean of 49.8 years. Symptom duration ranged from 2 months to a year. Examination revealed ulcerated and bleeding grey to black tumours of varying sizes located predominantly in the hard palate in nine cases with lymph nodes (submandibular and cervical) enlargement. Palatal melanoma has a rapid growth rate and most patients present with advanced disease which has poorer prognosis. Its classification and treatment is still based on the cutaneous disease. Early disease is often asymptomatic thus awareness and knowledge of its biological behaviour by attending clinicians will aid prompt diagnosis and also reduce morbidity and mortality of this aggressive tumour

Keywords:

Melanoma, extracutaneous, female, palate,

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