Vivek PAİTHANKAR, Shailesh KEWATKAR, Supriya DESHPANDE, Manwendra KARCHULİ

Effect of Ailanthus Excelsa Against Cyclophosphamide Induced Genotoxicity

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Effect of Ailanthus Excelsa Against Cyclophosphamide Induced Genotoxicity

Mutagenicity refers to the induction of permanent transmissible changes in the amount or structure of the genetic material of cells or organisms. These changes may involve a single gene or gene segment, a block of genes or chromosomes.

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1. EFSA Scientific Committee; Draft Scientific Opinion on Genotoxicity Testing Strategies applicable in food and feed safety assessement. European Food Safety Authority (2011). Available online: www.efsa.europa.eu.
2. Guidance on genotoxicity testing and data interpretation for pharmaceuticals intended for human use, international conference on harmonisation of technical requirements for registration of pharmaceuticals for human use, 2008, S2(R1).
3. Suchitra P, Suresh J, Archana T. Therapeutic use of cyclophosphamide and its cytotoxic action : A challenge for researchers. J Pharmacy Res 2011;4(8):2755-7.
4. Agrawal RC. In: Induction of chromosomal aberrations by propoxur in bone marrow cell. Biomedical and Environmental sciences.pp 292-295.