Ahmad SETTİN, Mohamed Abdel-Halem HELALY, El-Sayed Zaki HATATA, Eman Fathi IBRAHEM, Afaf ALSAİD, Ibrahim Ahmed Abd EL-AAL, Megahed ABU-ELMAGD

Association of ıl-10 and ıl-6 gene polymorphisms with type 2 diabetes mellitus among egyptian patients

Son yıllarda bazı sitokinlerin insülin duyarlı glikoz alınımı ile ilişkiye girebilme ile birlikte insülin direnci meydana getirebilme yeteneğine sahip olduğu bildirilmiştir. Mısırlı tip 2 diabetli hastalarda L-10 1082 and IL-6 174 genetik poliformizm ilişkisini test etmek için ortalama yaşı 57 olan 69 hasta (31 E ve 38 K) ve sağlıklı 98 kişi Nil deltasından çalışmaya alındı. Kontrol grubu ile karşılaştırıldığında tip 2 diabetli hastalar yüksek oranda L-10 1082 GG genotipe (p

Mısır'lı hastalarda tip 2 diyabet ile ıl-10 ve ıl-6 gen poliformizmi arasındaki ilişki

Recent findings indicate that certain cytokines are capable of interfering with insulin sensitive glucose uptake and induce insulin resistance. To test for the association of IL-10 1082 and IL-6 174 genetic polymorphisms with type 2 diabetes mellitus in Egyptian patients. Participants included 69 cases with type 2 DM (31 males and 38 females) with a median age of 57 years in addition to 98 healthy unrelated controls from the Nile Delta region, Egypt. Compared to controls, cases with type 2 diabetes mellitus showed a highly significant increase in the frequency of IL-10 1082 GG genotype (p

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