Azeem S SHEİKH

80112

A Young Patient with Quadriplegia and Ophthalmoplegia

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A Young Patient with Quadriplegia and Ophthalmoplegia

A 24-year-old gentleman presented with a history of severe throbbing headache preceded by sore throat. He was noted to have a nasal twang and dysphagia. He progressively developed weakness of all four limbs associated with ophthalmoplegia. He, subsequently, had to be intubated and ventilated in view of the involvement of the respiratory muscles. His anti-GQ1b antibodies were positive and the diagnosis of Bickerstaff brainstem encephalitis associated with Miller Fisher Syndrome overlapping with Guillain-Barre syndrome was confirmed. He was treated with intravenous Immunoglobulins 0.4 gm/kg/day for 5 days which resulted in a gradual recovery from his neurologic weakness.
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  • Ropper AH. The Guillain-Barre Syndrome. N Engl J Med 1992; 326:11306.
  • Mori M, Kuwabara S, Fukutake T, Yuki N, Hattori T. Clinical features and prognosis of Miller Fisher syndrome. Neurology 2001; 56:1104-6.
  • Fisher M. An usual variant of acute idiopathic polyneuritis (Syndrome of ophthalmoplegia, ataxia and areflexia) N Eng J Med 1956; 255: 57-65.
  • Bickerstaff, ER. Brainstem Encephalitis: further observa- tions on a grave syndrome with benign prognosis. Br Med J 1957; 1: 1384-7. 276
European Journal of General Medicine-Cover
  • Yayın Aralığı: 4
  • Başlangıç: 2015
  • Yayıncı: Sağlık Bilimleri Araştırmaları Derneği
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