Toxic effects of water/alcoholic extract of Syzygium aromaticum on sperm quality, sex hormones and reproductive tissues in male mouse
Syzygium aromaticum was considered as an aphrodisiac agent; however, it may cause some side effects.
The aim of this study was to examine the effects of Syzygium aromaticum extract on male reproductive
system. To do this, forty male mice were divided into 5 groups: negative control was fed with vehicle,
positive control was fed with aphridite and three experimental groups were fed with 250, 500 and 1000
mg/kg/day of water/alcohol extract of S. aromaticum for 34 days. The sperm count and motility and also
the sex hormones level were assessed. The reproductive tissues were prepared histologically and studied
under the light microscope. The results indicated the high dose-treated animals showed a significant
decline in sperm count, motility and testosterone but a significant increase in estradiol concentration
compared with the control group. The seminiferous tubules of extract-treated animals contained fewer
sperms than in those of control animals. It seems that in spite of aphrodiastic activity of the Syzygium
aromaticum extract, it reduced spermatogenesis.
Keywords: Reproduction, Syzygium aromaticum, Sperm
Keywords:
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- ISSN: 2602-2575
- Yayın Aralığı: Yılda 2 Sayı
- Başlangıç: 1940
- Yayıncı: İstanbul Üniversitesi Yayınevi
Sayıdaki Diğer Makaleler
Farzaneh DEHGHANİ, Aseyeh HESHMATPOUR, Mohammad PANJEHSHAHİN, Tahereh TALAEİ-KHOZANİ
Betül OKUYAN, Fikret IZZETTİN, Özlem BİNGÖL-OZAKPİNAR, Pınar TURAN, Zarife OZDEMİR, Mesut Sancar, Zeynep CİRAKLİ, Philip CLARK, Feriha ERCAN
Endemik Centaurea arifolia Boiss. bitkisinin in Vitro üretimi
Elif YÜZBAŞIOĞLU, Eda DALYAN, Mehmet BONA, Gül ÖZ
Selda GEZGİNCİ-OKTAYOGLU, İsmet BURCU TURKYİLMAZ, Refiye YANARDAG, Sehnaz BOLKENT