Covid-19 is a viral disease that has recently become extremely dangerous and lethal. A severe inflammatory response develops as a result of the viral disease affecting the body. According to some research, the development of this response causes damage to various organs and tissues. Natural compounds may reduce or prevent the potential damage to the organism caused by this inflammatory response. Probiotics have powerful anti-inflammatory properties, according to new research. As a result, the potential anti-inflammatory effects of probiotics in Covid-19 disease will be discussed in this study.