We read with interest the research article prepared by Duyan et al. and titled "Is it Possible to Predict High-Risk Patients in Acute Pulmonary Embolism with Systemic Immune-Inflammation Index" published in the last issue of 2022 of your journal. They reported that it is a more valuable biomarker in predicting high-risk acute pulmonary embolism than other combined hematological indices. We thank the authors and editorial board for this informative and interesting article.