Antimicrobial activity of Drosera peltate J.E.Sm extracts against clinically isolated human cariogenic pathogens—an in vitro study

Oral cariogenic bacterial infection causes development of dental caries. This caries become intensely painful and hard to eradicate these causing agents without side effect. The plant and the phytoconstituents have a promising therapeutic potential in the management of dental caries treatment. The study aimed to evaluate antimicrobial activity of chloroform, ethanol and aqueous extracts of Drosera peltata J.E.Sm against clinically isolated human cariogenic pathogens. Chloroform, ethanol and aqueous extracts of Drosera peltata J.E.Sm were tested against the Streptococcus mutans (a bacterium) and Candida albicans (a non-filamentous fungus). They are causing dental caries and were isolated from cariesinfected patients. The above three extracts showed antimicrobial activity against both S. mutans and C. albicans. The zone ofinhibition was found to be high with chloroform extract of D. peltata. It also showed the minimum inhibitory concentration against S. mutans than the aqueous and ethanol extracts to Mueller Hinton Broth (MHB).The plant Drosera peltata J.E.Sm showed antimicrobial activity against dental caries such asS. mutans and C. albicans. It would be havetherapeutic use for dental caries and other oral infections.

Keywords:

Drosera peltata,

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Duraipandiyan V, Ignacimuthu S 2007. Antibacterial and antifungal activity of Cassia fistula L.: an ethnomedicinal plant. J. Ethnopharmacol. 112(3): 590–594. Paper DH, Karall E, Kremser M, Krenn L 2005. Comparison of the antiinflammatory effects of Drosera rotundifolia and Drosera madagascariensis in the HET-CAM assay. Phytotherapy Research. 19(4): 323–326.
Raju A, Christina AJM, Anita Murali 2013a. In vitro antioxidant and anticancer activity studies on Drosera indica L. (Droseraceae). Adv. Pharm. Bull. 3(1): 115-120. Raju A, Christina AJM, Anita Murali 2013b. Effect of Drosera burmannii Vahl on metabolic syndrome developed in Ehrlich Ascites Carcinoma (EAC) bearing mice. Phytopharmacology. 4(1): 53-60.
Raju A, Seeja S Raj, Balaji VR 2016a. An in vitro evaluation of antimicrobial activity of Drosera peltate J.E.Sm against clinically isolated human periodontal pathogens. Journal of international research in medical and pharmaceutical sciences. 10(3): 115-120.
Raju Asirvatham, Seeja S Raj, Arokiasamy Josphin Maria Christina 2016b. Modulatory effect of Drosera peltate J.E.Sm on development of metabolic syndrome in tumor bearing mice. Indonesian J. Pharm. 27(4): 203-210.
Shyla JebashreeH, Jayasurya Kingsley S, Emmanuel S Sathish, Deva priya D 2011. Antimicrobial activity of few medicinal plants against clinically isolated human cariogenic pathogens—An in vitro Study. ISRN Dentistry. 1-6
Singh J, Kumar A, Budhiraja S, Hooda A 2007. Ethnomedicine: use in dental caries. Braz. J.Oral.Sci. 6 (21): 1308-1312.
Sunaina Shetty, Biju Thomas, Veena Shetty, Rahul Bhandary, Raghavendra M Shetty 2013. An invitro evaluation of the efficacy of garlic extract as an antimicrobial agent on periodontal pathogens: A microbiological study. AYU. 34(4): 445-451.