Gül Fatma YARIM, Gülay ÇİFTCİ, Sena ÇENESİZ, Cevat NİSBET, Erol HANDEMİR, Taraneh ÖNCEL

Toksoplazma Gondii Yönünden Seropozitif Köpeklerin Serum Total Sialik Asit ve Seruloplazmin Düzeylerinin Belirlenmesi

Bu çalışmada, İstanbul’un çeşitli barınaklarında bulunan ve Toxoplasma gondii seropozitif olan köpeklerin serum sialik asit (TSA) ve seruloplazmin (CP) düzeylerinin araştırılması ve bu düzeylerin arasında olası ilişkinin incelenmesi hedeflendi. Bu amaçla indirekt floresan antikor testi (IFAT) sonuçlarına göre T. gondii seronegatif bulunan 15 sağlıklı köpek ile seropozitif bulunan 25 enfekte köpekten kan örnekleri alındı ve serumları çıkarıldı. TSA ve CP değerleri ölçüldü. Yapılan analizlerde hasta ve kontrol gruba ait TSA düzeyleri sırası ile 17.20±0.55 mg/dl ve 15.97±0.55 mg/dl olarak tespit edildi. Buna göre hasta ve kontrol gruba ait serum TSA düzeyleri arasında istatistiksel olarak önemli bir fark bulunmadı (P>0.05). Serum SP ortalamaları hasta ve kontrol gruplarda sırasıyla 16.49±1.11 mg/dl ve 10.28±1.63 mg/dl olarak bulundu. Hasta grubun serum CP düzeyleri kontrol grubuyla karşılaştırıldığında anlamlı olarak yüksek bulundu (P

Anahtar Kelimeler:

Etlik Veteriner Mikrobiyoloji Dergisi, Toksoplazma Gondii, Köpek, Seruloplazma, Sialik Asit, Cevat NİSBET, Sena ÇENESİZ, Taraneh öncel, Gül Fatma YARIM, Gülay ÇİFTCİ, Erol HANDEMİR, 2010

Determination of Serum Total Sialic Acid and Ceruloplasmin Concentrations in Toxoplasma Gondii Seropositive Dogs

This study aimed to investigate serum total sialic acid (TSA) and ceruloplasmin (CP) levels and their possible correlation in Toxoplasma gondii seropositive dogs. The study was conducted on the dogs that had been kept in doghouses located in the province of Istanbul. Based upon indirect fluorescence antibody test (IFAT) results, 15 T. gondii seronegative dogs and 25 seropositive infected dogs were included in the study. Blood samples were collected from each dog and serums were obtained. Subsequently, TSA and CP concentrations were measured. For serum TSA concentration, no significant difference was found between control (17.20±0.55 mg/dl) and infected dogs (15.97±0.55 mg/dl) (p>0.05). On the other hand, serum CP concentration was significantly higher in seropositive dogs (16.49±1.11 mg/dl) compared to control dogs (10.28 ±1.63 mg/dl) (p

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