Bu çalışmada, Bursa ilinde 82 adet sokak köpeğinden alınan kan senunu Mikroskopik Aglutinasyon Testi (MAT) ile Leptospira antikorları yönünden incelendi . L.grippotvphosa (serovar moskova-V) .L. bali um (sv. Mus-127), L.poınona (sv.pomona), L.canicola (sv.utrecht-IV), L.icterohaemorrhagiae(sv. icterohaemorrhagiae-RGA) antijenlerinin kullanıldığı MAT'inde 9 adet (%10. 97) serum sadece L. icterohaemorrhagiae (sv. icterohaemorrhagie-RGA) seratipi ile pozitif reaksiyon verdi. Pozitif senımiarın titreleri 1:100 ( 4/9), 1:200 (2/9), 1:400 (2/9), ve 1:800 ( 1/9) olarak bulundu. infeksiyon oranı dişi köpeklerde %13.72, erkek köpeklerde %6.45 olarak bulundu . 1-4 yaş arası köpeklerde infeksiyon oranının (%15.09), I yaşından küçük köpeklerden (%4.34) daha yüksek olduğu saptandı.
In this study, sera obtained from 82 stray dogs in Bursa were cxamined by the Mieroscopic Agglutination Test (MAT) for Leptospiral antibodies. Ninc sera (10.97%) were positive only with serotype L.icterohaemorrhagiae -RGA in MAT which L.grippotvphosa (sv. Moskova-V). L.ballum (sv Mus-127), L.pomona (sv.pomona), L.canicola (sv. utrecht-IV) and L.icterohaemorrhagiae (sv. Jet. RGA) serotypes \:vere used as antigens. Positive sera titres were I: I 00 (4/9), 1:200 (2/9), 1:400 (2/9)and 1:800 ( 1/9). Infection rates were found 13.72% in female dogs, 6.45% in malc dogs. It was datermined that the infection rate was highe
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ANONYM (Australia, Veterinary Pathology Services ), ( 1989) : Canine Leptospirosis- A Reeınerging Disease? Australian Veteıinary Practitioner, 19(3), 154.
ANDREWES, C. H. and WALTON, J. R.( 1977) : Animal and Human Health Viral and Bacteıial Zoonoses, Brander,G.C.,Cassell and Collier, London, 108- 111.
ARDA, M., MİNBAY, A., LELOGLU, N., AYDIN, N., AKAY; Ö. (1992): Özel Mikrobiyoloji, Atatürk Üniv. Yayınları , No:741. Erzunım, 456- 460.
ARİMİTSU, Y., FUKUMURA, K., SHİNGAKİ, Y. (1989) : Distribution of Leptospirozis among stray dogs in the Okinawa islands, Japan: Comparison of the microcapsule and microscopic agglutination tests, Br. Vet. J., 145,473 .
ARİMİTSU, Y., HARİTANİ, K., ISHIGURO, N. and KOBAYASHİ, S. ( 1989) : Detection of antibodies to Leptospirosis in experimentally infected dogs us ing the Micocapsule Agglutination Test, B r. Vet. J ., 145,356-361.
ARİMİTSU, Y. and MATUHASi, T. (1987) : Seradiagnosis of Leptospirosis in China by the one-point MCA method, Epidem, InL99,393- 398.
BLO BEL, H. and SCHLİEBER, T. (1985) : Leptospira, Handbuch der bacteriellen infektionen beitieren, 5,135- 136.
DİCKESON D., LOVE D.N. (1993): A serological survey of dogs, cats and horses in south-castern Australia for leptospiral antibodies, Aust. Vet.J .,70 (10), 389-390.
ELLIS, W. A. (1986): Leptospirosis, J. Smail Anim. Practice, 27 ,683- 390.
EVERARD, C.O.R., JONES, C.J., INNİSS, V.A., CARRİNGTON, D.G. and VAUGHAN A.W.(I987): Leptospirosis in dogs on Barbados, Isr.J.Vet.Med.,43(4), 288-295.
FAİNE, S. (1982) :Guidelines for control of Leptospirosis, Seetion B- 138, World Health Organization, Geneva.
GİLLESPİE, J.H., TİMONEY, J.F. (1981): Hagan anc;i Bruner's lnfectious Diseascs of Domestic Animal s, Seventh Edition, Comeli University Press, United Kingdom, 67-68.
HARTMAN, E.G., VAN DEN INGH, T.S.G.A.M., ROTHUİZEN, J. ( 1986) : Clinical, Pathological and Serogical features of spontaneous canine Leptospirosis. An evaluation of the IgM-and lgG-specifıc ELISA., Vet. Immun. Immunopath., 13,261-271.
HATHAWAY, S.C., LİTTLE, T.W.A., HEADLAM, S.A. (1983): Infection of free-living camİvares with leptospires of the Australis serogrup, Vet.Rec., 113,233-235.
HATHAWAY, S.C., LİTTLE, T.W.A., STEVENS, A.E.(1983) : Seravar identifıcation ofleptospires of the Australis serogrup isolated from freeliving and domestic species in the United Kingdom, Res.Vet.Sci .,35,64-68.
JOHNSON, R.C. and FAİNE, S. (1984) : Leptospiracea, Bargey's Manual of systematic Hacteriology Vol .1 , Krieg N. R., Williams & Wilkins, USA, 62-67.
MA LO NE, E. ( 1994) : Leptospirosis-an im portant zoonosis, Iris h Vet.J., 47(6),272-273
MİCHNA, S.W. (1970) : Leptospirosis, Vet.Rec.,86,484-496.
PRESCOTT, J.F., FERRİER, R.L., NİCHOLSON, V.M., JOHNSTON, K. M., HOFF, B. ( 1991): Is canine leptospirosis underdiagnosed in southem Ortario? A casereport and serological survey, Can.Vet.J.,32,481- 486
PRİTCHARD, D.G. (1990) : Spirochaetal and Leptospiral diseases, Topley and Wilson's Principles ofBacteriology, Virology and lrnmunity, Eighth Ed., Vo1.3 ,Bacterial Diseases, Geoffrey R. Smith, Charles S.F., Easman, Butler & Tanner Ltd., Great Britain, 632-633 .
ROTHWELL, J. T. (1990) : Serum agglutinating antibodies to Leptospira interrogans serovar canicola presumed due to seravar robinsani infection in an Australian dog, Australian Vet. J.,67(6),232.
SCHMİDT, D.R., WİNN, R.E., KEEFE, T.J. ( 1989): Lcptospirosis, Epideıniological features ofa sporadic qase, Arch. Intem.Med., 149, 1878-1880.
SÜMBÜLOVA, K., SÜMBÜLOVA, V. ( 1995): Biyoistatistik, Özdemir yay ıncılık, Ankara, 156-167. 24. VENKANATARAMAN, K.S. and NEDUNCHELLİYAN, S.(1992): Epideıniology of an outbreak of Leptospirosis in man and dog, Comp. Immun. Microbiol. Infect. Dis., 15(4), 243-247.
VENKANATARAMAN, K.S. and NEDUNCHELLİYAN, S.(1993): Seroepideıniology of canine leptospirosis in Madras city, Inciian Journal of Animal Sciences,63(2), 150-152.
WATSON, A.D.J. (199 1): Leptospirra interrogans seravar bratislava infection, J .A.V.M.A., 199(10), 1239.
WİNERALS, C.G., CHAN, L., CONGLAN, J.D., LEDİNGHAM, J.G.G., OLiVER, D.O. (1984) : Acute renal failure due to Leptospirosis: Clinical features and outcoıne in six cases, Quarterly Journal of Medicine, 212, 487-495 .