Balıkesir Yöresinde Snirsel Semptom Gösteren Koyunlarda Listeria Encephalitis Teşhisi

Bu çalışma Balıkesir ilinde koyunlarda, sinirsel semptomlarla seyreden hastalığın incelenmesi amacıyla yapıldı. Formolde tespit edilmiş ve parafinde bloklanmış beyin dokusünda, histopatolojik ve immunoperoksidaz boyama teknikleri kullanılarak, Listeria encephalitis tespit edildi. Histopatolojik olarak karakteristik lezyonlar, pons cerebri, cerebellum, m. oblongatada görüldü. Streptavidin-biotin immunoperoksidaz boyamalarda; mikroapselerin şekillendiği adaklarda, löykositlerin ve az olarak da makrofajların siteplazmaları içinde, Listeria monocytogenes antijeni tespit edildi.

Anahtar Kelimeler:

Etlik Veteriner Mikrobiyoloji Dergisi, Listeria Encephelitis, Koyun, Balıkesir, 1999

Diagnosis of Listeria Encephalitis Characterised by Nervous Symptoms in Sheep in Balıkesir Region

In this study the disease which is characterised by nervous symptoms in sheep in Balıkesir province was investigated. Listeria encephalitis was detected in formaline fixed and paraffin embedded brain tissues using by histopathologic and immunoperoxidase methods. Typical histopathological lesions were observed in pons cerebri, cerebellum, m.oblongata. L. monocytogenes antigens were determinated in leucocytes and macrophages in the microabscesses foci. In streptavidin-biotin immunoperoxydase stained slides bacterial antigens were less in macrophages than leucocytes.

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