Fatih GÖĞER, Ayla KAYA, Muhittin DİNÇ, Süleyman Doğu DOĞU

PHENOLIC COMPOUNDS DETERMINATION AND ANTIOXIDANT ACTIVITY OF TEUCRIUM CAVERNARUM

ABSTRACT The current study was aimed to determine phenolic compounds profile and antioxidant activity of 70% MeOH extract of Teucrium cavernarum P.H. Davis which is an endemic plant of Turkey. According to LC-MS/MS analysis of the extract, forsythoside A, forsythoside B, luteolin-7-gucoside, cirsimaritin and cirsiliol were determined as the major compounds. The total phenolic and radical scavenging activities of the extract were also determined. According to antioxidant activity results, IC50 value of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect was determined as 0.12 ±0.01 mg/mL. 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity was also determined as 1.2 mM trolox equivalent (TEAC).

Anahtar Kelimeler:

Teucrium cavernarum, Antioxidant activity, LC-MS/MS, Phenolic

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