COVID-19 ve Ruh Sağlığı: Güncel Araştırmalar Bize Ne Gösteriyor?

SARS-CoV-2 enfeksiyonunun neden olduğu COVID-19 tüm dünyayı 2019 sonundan bu yana etkisi altına almıştır. Hastalığın birden çok organ ve sistemi farklı şekilde etkilendiği bilinmektedir. Bu etkiler içinde ruh sağlığına olan etkileri de doğrudan ve dolaylı şekilde olmak üzere saymak mümkündür. Dolaylı etkilerden pandeminin günlük hayata etkileri ve bunun sonuçları, doğrudan etkilerden de enfeksiyonu geçirmiş bireyler üzerinde gözlenen etkiler sayılabilir. Tüm bu etkiler tek şekilde ortaya çıkmamakta ve ruh sağlığını üzerinde farklı yönlerden bozulmalara yol açmaktadır. Bu bozukluklara duygudurum bozuklukları, uyku bozuklukları, anksiyete bozuklukları ve psikotik bozukluklar örnek verilebilir. Ne yazık ki enfeksiyonun ortaya çıkardığı etkilerin mekanizmaları ve temelleri henüz aydınlatılabilmiş değildir. Ancak korunma yolları ve olası klinik tabloların neler olabileceğine dair araştırmalar pandeminin başlangıcından bu yana sürdürülmekte ve yayınlanmaktadır. Bu gözden geçirme yazısında mevcut araştırmaların ışığında COVID-19 pandemisinin ruh sağlığına etkileri özetlenmiştir.

COVID-19 and Mental Health: What do Current Research Show Us?

COVID-19, caused by SARS-CoV-2 infection, has affected the whole world since the end of 2019. It is known that the disease affects multiple organs and systems in different ways. Among these effects, it is possible to count both direct and indirect effects on mental health too. Among the indirect effects, the effects of the pandemic on daily life and its consequences, and the direct effects on individuals who have been infected can be counted. All these effects do not manifest uniformly and cause deterioration in different aspects of mental health. Examples of these disorders are mood disorders, sleep disorders, anxiety disorders and psychotic disorders. Unfortunately, the mechanisms and basis of the effects of the infection have not been clarified yet. However, research on ways of protection and possible clinical manifestations has been carried out and published since the beginning of the pandemic. In this review, the effects of the COVID-19 pandemic on mental health was summarized in light of current research.

___

  • 1. Lehmann M, Bruenahl CA, Löwe B, et al. Ebola and psychological stress of health care professionals. Emerg Infect Dis. 2015;21(5):913-914.
  • 2. Keita MM, Taverne B, Sy Savané S, et al. Depressive symptoms among survivors of Ebola virus disease in Conakry (Guinea): preliminary results of the PostEboGui cohort. BMC Psychiatry. 2017;17(1):127.
  • 3. Torales J, O'Higgins M, Castaldelli-Maia JM, et al. The outbreak of COVID-19 coronavirus and its impact on global mental health. Int J Soc Psychiatry. 2020;66(4):317-320.
  • 4. Mukaetova-Ladinska, E.B., Kronenberg, G. Psychological and neuropsychiatric implications of COVID-19. Eur Arch Psychiatry Clin Neurosci. 2021;271:235–248.
  • 5. Cooke JE, Eirich R, Racine N, et al. Prevalence of posttraumatic and general psychological stress during COVID-19: A rapid review and meta-analysis. Psychiatry Res. 2020;292:113347.
  • 6. Rossi R, Socci V, Talevi D, et al. COVID-19 Pandemic and Lockdown Measures Impact on Mental Health Among the General Population in Italy. Front Psychiatry. 2020;11:790..
  • 7. Salari N, Hosseinian-Far A, Jalali R, et al. Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: a systematic review and meta-analysis. Global Health. 2020;16(1):57.
  • 8. Jahrami H, BaHammam AS, Bragazzi NL, et al. Sleep problems during the COVID-19 pandemic by population: a systematic review and meta-analysis. J Clin Sleep Med. 2021;17(2):299-313.
  • 9. Gobbi S, Płomecka MB, Ashraf Z, et al. Worsening of Preexisting Psychiatric Conditions During the COVID-19 Pandemic. Front Psychiatry. 2020;11:581426.
  • 10. Deng J, Zhou F, Hou W, et al. The prevalence of depressive symptoms, anxiety symptoms and sleep disturbance in higher education students during the COVID-19 pandemic: A systematic review and meta-analysis. Psychiatry Res. 2021;301:113863.
  • 11. Mamun MA, Sakib N, Gozal D, et al. The COVID-19 pandemic and serious psychological consequences in Bangladesh: A population-based nationwide study. J Affect Disord.
  • 12. Xiong J, Lipsitz O, Nasri F, et al. Impact of COVID-19 pandemic on mental health in the general population: A systematic review. J Affect Disord. 2020;277:55-64.
  • 13. Brunoni AR, Suen PJC, Bacchi PS, et al. Prevalence and risk factors of psychiatric symptoms and diagnoses before and during the COVID-19 pandemic: findings from the ELSA-Brasil COVID-19 mental health cohort [published online ahead of print, 2021 Apr 21]. Psychol Med. 2021;1-12. doi:10.1017/S0033291721001719
  • 14. Liu RT, Bettis AH, Burke TA. Characterizing the phenomenology of passive suicidal ideation: a systematic review and meta-analysis of its prevalence, psychiatric comorbidity, correlates, and comparisons with active suicidal ideation. Psychol Med. 2020;50(3):367-383.
  • 15. Dubé JP, Smith MM, Sherry SB, et al. Suicide behaviors during the COVID-19 pandemic: A meta-analysis of 54 studies. Psychiatry Res. 2021;301:113998.
  • 16. Morina N, Kip A, Hoppen TH, et al. Potential impact of physical distancing on physical and mental health: a rapid narrative umbrella review of meta-analyses on the link between social connection and health. BMJ Open. 2021;11(3):e042335.
  • 17. John A, Okolie C, Eyles E, et al. The impact of the COVID-19 pandemic on self-harm and suicidal behaviour: a living systematic review. F1000Res. 2020;9:1097.
  • 18. Dubey MJ, Ghosh R, Chatterjee S, et al. COVID-19 and addiction. Diabetes Metab Syndr. 2020;14(5):817-823.
  • 19. Ornell F, Moura HF, Scherer JN, et al. The COVID-19 pandemic and its impact on substance use: Implications for prevention and treatment. Psychiatry Res. 2020;289:113096.
  • 20. Santabárbara J, Bueno-Notivol J, Lipnicki DM, et al. Prevalence of anxiety in health care professionals during the COVID-19 pandemic: A rapid systematic review (on published articles in Medline) with meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry. 2021;107:110244.
  • 21. Salari N, Khazaie H, Hosseinian-Far A, et al. The prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients: a systematic review and meta-regression. Hum Resour Health. 2020;18(1):100.
  • 22. Deng Y, Chen Y, Zhang B. Different prevalence trend of depression and anxiety among healthcare workers and general public before and after the peak of COVID-19 occurred in China: A meta-analysis. Asian J Psychiatr. 2021;56:102547.
  • 23. Greenberg N, Weston D, Hall C, et al. Mental health of staff working in intensive care during Covid-19. Occup Med (Lond). 2021;71(2):62-67.
  • 24. Tengilimoğlu D, Zekioğlu A, Tosun N, et al. Impacts of COVID-19 pandemic period on depression, anxiety and stress levels of the healthcare employees in Turkey. Leg Med (Tokyo). 2021;48:101811.
  • 25. Şahin MK, Aker S, Şahin G, et al. Prevalence of Depression, Anxiety, Distress and Insomnia and Related Factors in Healthcare Workers During COVID-19 Pandemic in Turkey. J Community Health. 2020;45(6):1168-1177.
  • 26. Elbay RY, Kurtulmuş A, Arpacıoğlu S, et al. Depression, anxiety, stress levels of physicians and associated factors in Covid-19 pandemics. Psychiatry Res. 2020;290:113130.
  • 27. Li W, Zhao N, Yan X, et al. The prevalence of depressive and anxiety symptoms and their associations with quality of life among clinically stable older patients with psychiatric disorders during the COVID-19 pandemic. Transl Psychiatry. 2021;11(1):75.
  • 28. Yurumez Korkmaz B, Gemci E, Cosarderelioglu C, et al. Attitudes of a geriatric population towards risks about COVID-19 pandemic: in the context of anxiety and depression [published online ahead of print, 2021 Jun 15]. Psychogeriatrics. 2021;10.1111/psyg.12731. doi:10.1111/psyg.12731.
  • 29. Chmielewska B, Barratt I, Townsend R, et al. Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis [published correction appears in Lancet Glob Health. 2021 Jun;9(6):e758]. Lancet Glob Health. 2021;9(6):e759-e772.
  • 30. Shorey SY, Ng ED, Chee CYI. Anxiety and depressive symptoms of women in the perinatal period during the COVID-19 pandemic: A systematic review and meta-analysis [published online ahead of print, 2021 May 8]. Scand J Public Health. 2021;14034948211011793. doi:10.1177/14034948211011793.
  • 31. Minihan E, Gavin B, Kelly BD, McNicholas F. COVID-19, mental health and psychological first aid. Ir J Psychol Med. 2020;37(4):259-263.
  • 32. Neelam K, Duddu V, Anyim N, Neelam J, Lewis S. Pandemics and pre-existing mental illness: A systematic review and meta-analysis. Brain Behav Immun Health. 2021;10:100177.
  • 33. Mazza MG, De Lorenzo R, Conte C, et al. Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors. Brain Behav Immun. 2020;89:594-600.
  • 34. Deng J, Zhou F, Hou W, et al. The prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients: a meta-analysis. Ann N Y Acad Sci. 2021;1486(1):90-111.
  • 35. Qi R, Chen W, Liu S, et al. Psychological morbidities and fatigue in patients with confirmed COVID-19 during disease outbreak: prevalence and associated biopsychosocial risk factors. Preprint. medRxiv. 2020;2020.05.08.20031666.
  • 36. Dantzer R. Neuroimmune Interactions: From the Brain to the Immune System and Vice Versa. Physiol Rev. 2018;98(1):477-504.
  • 37. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [published correction appears in Lancet. 2020 Jan 30;:]. Lancet. 2020;395(10223):497-506.
  • 38. Parra A, Juanes A, Losada CP, et al. Psychotic symptoms in COVID-19 patients. A retrospective descriptive study. Psychiatry Res. 2020;291:113254.
  • 39. Costardi CG, Cavalcante DA, Macêdo MA, et al. COVID 19 pandemic and distinct patterns of psychotic outbreaks [published online ahead of print, 2021 May 21]. Trends Psychiatry Psychother. 2021;10.47626/2237-6089-2020-0188. doi:10.47626/2237-6089-2020-0188.
  • 40. Marouda K, Mantonakis L, Kollias K. Brief psychotic disorder with delusion content related to the COVID-19 outbreak. Psychiatriki. 2021;32(1):79-82.
  • 41. Parker C, Slan A, Shalev D, et al. Abrupt Late-onset Psychosis as a Presentation of Coronavirus 2019 Disease (COVID-19): A Longitudinal Case Report. J Psychiatr Pract. 2021;27(2):131-136.
  • 42. Brown E, Gray R, Lo Monaco S, et al. The potential impact of COVID-19 on psychosis: A rapid review of contemporary epidemic and pandemic research. Schizophr Res. 2020;222:79-87.
  • 43. Ennis L, Rose D, Denis M, et al. Can't surf, won't surf: the digital divide in mental health. J Ment Health. 2012;21(4):395-403.
  • 44. Kozloff N, Mulsant BH, Stergiopoulos V, et al. The COVID-19 Global Pandemic: Implications for People With Schizophrenia and Related Disorders. Schizophr Bull. 2020;46(4):752-757.
  • 45. Mcloughlin BC, Miles A, Webb TE, et al. Functional and cognitive outcomes after COVID-19 delirium. Eur Geriatr Med. 2020;11(5):857-862.
  • 46. Helms J, Kremer S, Merdji H, et al. Delirium and encephalopathy in severe COVID-19: a cohort analysis of ICU patients. Crit Care. 2020;24(1):491.
  • 47. Pranata R, Huang I, Lim MA, et al. Delirium and Mortality in Coronavirus Disease 2019 (COVID-19) - A Systematic Review and Meta-analysis. Arch Gerontol Geriatr. 2021;95:104388.
  • 48. Baller EB, Hogan CS, Fusunyan MA, et al. Neurocovid: Pharmacological Recommendations for Delirium Associated With COVID-19. Psychosomatics. 2020;61(6):585-596.
  • 49. Zambrelli E, Canevini M, Gambini O, et al. Delirium and sleep disturbances in COVID-19: a possible role for melatonin in hospitalized patients?. Sleep Med. 2020;70:111.
  • 50. Hariyanto TI, Putri C, Arisa J, et al. Dementia and outcomes from coronavirus disease 2019 (COVID-19) pneumonia: A systematic review and meta-analysis. Arch Gerontol Geriatr. 2021;93:104299.
  • 51. Liu N, Sun J, Wang X, et al. The Impact of Dementia on the Clinical Outcome of COVID-19: A Systematic Review and Meta-Analysis. J Alzheimers Dis. 2020;78(4):1775-1782.
  • 52. Lee SW, Yang JM, Moon SY, et al. Association between mental illness and COVID-19 susceptibility and clinical outcomes in South Korea: a nationwide cohort study. Lancet Psychiatry. 2020;7(12):1025-1031.
  • 53. Zhang K, Zhou X, Liu H, et al. Treatment concerns for psychiatric symptoms in patients with COVID-19 with or without psychiatric disorders. Br J Psychiatry. 2020;217(1):351.
  • 54. Luykx JJ, van Veen SMP, Risselada A, et al. Safe and informed prescribing of psychotropic medication during the COVID-19 pandemic. Br J Psychiatry. 2020;217(3):471-474.
  • 55. Siskind D, Honer WG, Clark S, et al. Consensus statement on the use of clozapine during the COVID-19 pandemic. J Psychiatry Neurosci. 2020;45(3):222-223.
  • 56. Brooks SK, Webster RK, Smith LE, et al. The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet. 2020;395(10227):912-920.
  • 57. Ding H, He F, Lu YG, et al. Effects of non-drug interventions on depression, anxiety and sleep in COVID-19 patients: a systematic review and meta-analysis. Eur Rev Med Pharmacol Sci. 2021;25(2):1087-1096.
  • 58. Weiner L, Berna F, Nourry N, et al. Efficacy of an online cognitive behavioral therapy program developed for healthcare workers during the COVID-19 pandemic: the REduction of STress (REST) study protocol for a randomized controlled trial. Trials. 2020;21(1):870.
  • 59. Galea S, Merchant RM, Lurie N. The Mental Health Consequences of COVID-19 and Physical Distancing: The Need for Prevention and Early Intervention. JAMA Intern Med. 2020;180(6):817-818.
Eskisehir Medical Journal-Cover
  • ISSN: 2718-0948
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2020
  • Yayıncı: Eskişehir Şehir Hastanesi
Sayıdaki Diğer Makaleler

Çocuk Önkol Çift Kemik Kırıklarında Kapalı Redüksiyon ve Kanal-içi Elastik Çivileme. Klinik ve Radyolojik Sonuçlar

Zeynel Mert ASFUROĞLU, Ahmet KÜÇÜK, Nusret KÖSE

Akut konjestif kalp yetmezliğine neden olan dev sol atriyum: bir olgu sunumu

Murat DUYAN, Serhat GÜNLÜ, Ali SARIDAŞ, Resmiye Nur OKUDAN, İbrahim Ulaş ÖZTURAN

Kalıcı Diyaliz Kateteri Malpozisyonu Sonrası Tanı Alan Nadir Bir Vaka: Persistan Sol Superior Vena Kava

İbrahim Çağrı KAYA

Covid-19 Pandemisi ve Diyabetes Mellitus Etkileşimi

Sevilay Süreyya ERMİS

COVID-19 ve Ruh Sağlığı: Güncel Araştırmalar Bize Ne Gösteriyor?

Gamze GÜRCAN, Şükrü Alperen KORKMAZ, Şule BIÇAKCI AY, Ahmet GÜRCAN

Tip 2 Diyabet Mellitus Hastalarının Yaşadığı Kendini İzleme ve İlaç Engellerinin HbA1c Düzeylerine Etkisi

Aysun TÜRE, Nilüfer DEMİRSOY, Özge GÖDEK

Streptococcus porcinus Endokarditi: İnsanlarda Bildirilen İlk Olgu

Nur CANCAN GÜRSUL, Emre ÖZDEMİR

Çocukluk Çağı Lokal Yüksek Risk Ewing Sarkomu’nda Yüksek doz Kemoterapi ve Otolog Kök Hücre Nakli Ne Zaman Yapılmalı?: Olgu Sunumu

Hatice Mine ÇAKMAK, Yaşar BİLDİRİCİ, Fuzuli TUĞRUL, Meral BAHAR, Murat BALOĞLU, Müge GÜNDOĞDU

Göğüs Ağrısı ve/veya Anjinal Eşdeğer Semptomlarla Acil Servise Başvuran Kronik Böbrek Hastalarında İskemi-Modifiye Albüminin Akut Koroner Sendromlar Açısından Tanısal Değeri

İrfan GÖKÇEK, Bedriye Müge SÖNMEZ, Çiğdem YÜCEL, Mebrure Beyza GÖKÇEK, Fatih Alper AYYILDIZ

COVID-19 Salgını Sırasında Sağlık Profesyonelleri Tarafından Kullanılan Koruyucu Yüz Maskelerinin Rahatlığı ve Tolere Edilebilirliğinin Değerlendirilmesi

Murat DUYAN, İbrahim Ulaş ÖZTURAN, Mustafa Ayhan OZBEK, Hüseyin SEVIL, Ökkeş ZORTUK, Resmiye Nur OKUDAN, Fatih SELVİ, Aslıhan Yürüktümen ÜNAL, Yıldıray ÇETE