Hipoksi parametreleri, fiziksel değişkenler veobstrüktif uyku apnesinin şiddet derecesi
Objective:To determine the relation between hypoxia and physicalparameters in patients who had different levels of severity of obstructive sleep apnea (OSA). Methods:This was a retrospective, cross-sectional study of 259 menwho were evaluated with overnight polysomnography. Severity ofOSA was graded based on the apnea-hypopnea index (AHI):normal/simple snoring (n=31); mild OSA (n=70); moderate OSA(n=63); severe OSA (n=95). Patients with different severity weredivided into subgroups, based on having the lowest or highest valuesof the total sleep time with oxygen saturation
Hypoxia parameters, physical variables, and severity of obstructive sleep apnea
Objective:To determine the relation between hypoxia and physicalparameters in patients who had different levels of severity of obstructive sleep apnea (OSA). Methods:This was a retrospective, cross-sectional study of 259 menwho were evaluated with overnight polysomnography. Severity ofOSA was graded based on the apnea-hypopnea index (AHI):normal/simple snoring (n=31); mild OSA (n=70); moderate OSA(n=63); severe OSA (n=95). Patients with different severity weredivided into subgroups, based on having the lowest or highest valuesof the total sleep time with oxygen saturation
___
- 1. Schwab RJ, Goldberg AN. Upper airway assessment: radiographic and other imaging techniques. Otolaryngol Clin North Am 1998;31:931–68.
- 2. Thakkar K, Yao M. Diagnostic studies in obstructive sleep apnea. Otolaryngol Clin North Am 2007;40:785–805.
- 3. Ryan CM, Bradley TD. Pathogenesis of obstructive sleep apnea. J Appl Physiol (1985) 2005;99:2440–50.
- 4. Pang KP. Preface. In: Pang KP, Rotenberg BW, Woodson BT, editors. Textbook of advanced surgical techniques in snoring and obstructive sleep apnea. San Diego, CA: Plural Publishing; 2013. p. ix–x.
- 5. Dreher A, de la Chaux R, Klemens C, et al. Correlation between otorhinolaryngologic evaluation and severity of obstructive sleep apnea syndrome in snorers. Arch Otolaryngol Head Neck Surg 2005;131:95–8.
- 6. Bostanci A, Turhan M, Bozkurt S. Factors influencing sleep time with oxygen saturation below 90% in sleep-disordered breathing. Laryngoscope 2015;125:1008–12.
- 7. Roeslani RU, Woodson BT. Pathophysiology, signs, and symptoms of OSA. In: Pang KP, Rotenberg BW, Woodson BT, editors. Textbook of advanced surgical techniques in snoring and obstructive sleep apnea. San Diego, CA: Plural Publishing; 2013. p. 1–14.
- 8. Lavie L. Obstructive sleep apnoea syndrome – an oxidative stress disorder. Sleep Med Rev 2003;7:35–51.
- 9. Prabhakar NR, Kumar GK. Oxidative stress in the systemic and cellular responses to intermittent hypoxia. Biol Chem 2004;385: 217–21.
- 10. Iber C, Ancoli-Israel S, Chesson AL Jr, Quan SF. The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. Westchester, IL: American Academy of Sleep Medicine; 2007.
- 11. Kulkas A, Tiihonen P, Julkunen P, Mervaala E, Töyräs J. Novel parameters indicate significant differences in severity of obstructive sleep apnea with patients having similar apnea-hypopnea index. Med Biol Eng Comput 2013;51:697–708.
- 12. Li JR, Sun JJ, Zhang R, Li CF, Hu Y, Sun YM. Clinical value of TS90% in evaluation of hypoxemia in patients with obstructive sleep apnea/hypoventilation syndrome. [Article in Chinese] Zhonghua Yi Xue Za Zhi 2005;85:3115–7.
- 13. Li Q, Jin XJ. Correlations between the duration and frequency of sleep apnea episode and hypoxemia in patients with obstructive sleep apnea syndrome. [Article in Chinese] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2009;44:825–30.
- 14. Zhang XB, Zen HQ, Lin QC, Chen GP, Chen LD, Chen H. TST, as a polysomnographic variable, is superior to the apnea hypopnea index for evaluating intermittent hypoxia in severe obstructive sleep apnea. Eur Arch Otorhinolaryngol 2014;271: 2745–50.
- 15. Berry RB, Budhiraja R, Gottlieb DJ, et al.; American Academy of Sleep Medicine. Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 2012;8:597–619.
- 16. Gunnarsson SI, Peppard PE, Korcarz CE, et al. Minimal nocturnal oxygen saturation predicts future subclinical carotid atherosclerosis: the Wisconsin sleep cohort. J Sleep Res 2015;24:680–6.
- 17. Turhan M, Bostanci A, Bozkurt S. Predicting the outcome of modified tongue base suspension combined with uvulopalatopharyngoplasty. Eur Arch Otorhinolaryngol 2015;272: 3411–6.
- 18. Zhang J, Li Y, Cao X, et al. The combination of anatomy and physiology in predicting the outcomes of velopharyngeal surgery. Laryngoscope 2014;124:1718–23.