Olgu sunumu: Servikal özofagusta dev inlet patch

Servikal özofagus yerleşimli heterotopik gastrik mukoza, konjenital bir anomalidir. Semptomlar ve morfolojik değişiklikler, heterotopik gastrik mukozanın salgılamış olduğu asid hasarına bağlıdır. Bu odaktan malign transformasyon ve adenokarsinogenezis de oluşabilmektedir. Bu yazıda, daha önce bu kadar büyük düzeyde görmediğimiz servikal özofagustan torakal özofagusa kadar uzanan dev inlet patch olgusu sunulmuştur.

Anahtar Kelimeler:

Özofagus, inlet patch, heterotopik gastrik mukoza

Case report: giant inlet patch in cervical esophagus

Heterotopic gastric mucosa located in the cervical esophagus is a congenital anomaly. Symptoms and morphologic changes are associated with the destruction caused by the acid secreted from the heterotopic gastric mucosa. Malignant transformation and adenocarcinogenesis may also develop in these foci. In this case report, we present a patient who had a giant esophageal inlet patch, involving a large level of the cervical esophagus extending from the thoracic esophagus.

Keywords:

Esophagus, inlet patch, heterotopic gastric mucosa,

PDF

___

Tang P, McKinley MJ, Sporrer M, Kahn E. Inlet patch: prevalence, histo- logic type, and association with esophagitis, Barrett esophagus, and an- tritis. Arch Path Lab Med 2004; 128: 444-7.
Jacobs E, Dehou MF. Heterotopic gastric mucosa in the upper esopha- gus: a prospective study of 33 cases and review of literature. Endoscopy 1997; 29: 710-5.
Borhan-Manesh F, Farnum JB. Incidence of heterotopic gastric mucosa in the upper oesophagus. Gut 1991; 32: 968-72.
Korkut E, Bektaş M, Memmedzade F, et al. “Üst GİS Endoskopi Sırasın- da Inlet Patch Tanısını Atlıyor muyuz?” 23.Ulusal Gastroenteroloji Kon- gresi, 81, İstanbul, Türkiye 2006.
Poyrazoğlu OK, Bahçecioğlu İH, Dağlı AF, et al. Heterotopic gastric mu- cosa (inlet patch): endoscopic prevalence, histopathological, demograp- hical and clinical characteristics. Int J Clin Pract 2009; 63: 287-91.
Kekilli M, Sayılır A, Yeşil Y, et al. Servikal özofagustaki heterotopik gas- trik mukozanın endoskopik sıklığı; bir referans merkez çalışması. Aka- demik Gastroenteroloji Dergisi 2009; 8: 119-22.
von Rahden BH, Stein HJ, Becker K, et al. Heterotopic gastric mucosa of the esophagus: literature-review and proposal of a clinicopathologic clas- sification. Am J Gastroenterol 2004; 99: 543-51.
Lauwers GY, Scott GV, Vauthey JN. Adenocarcinoma of the upper esop- hagus arising in cervical ectopic gastric mucosa: rare evidence of malig- nant potential of so-called "inlet patch". Dig Dis Sci 1998; 43: 901-7.
Gutierrez O, Akamatsu T, Cardona H, et al. Helicobacter pylori and he- terotopic gastric mucosa in the upper esophagus (the inlet patch). Am J Gastroenterol 2003; 98: 1266-70.
Mann NS, Mann SK, Rachut E. Heterotopic gastric tissue in the duode- nal bulb. J Clin Gastroenterol 2000; 30: 303-6.
Xeropotamos N, Skopelitou AS, Batsis C, Kappas AM. Heterotopic gas- tric mucosa together with intestinal metaplasia and moderate dysplasia in the gall bladder: report of two clinically unusual cases with literature review. Gut 2001; 48: 719-23.
Berkelhammer C, Bhagavan M, Templeton A, et al. Gastric inlet patch containing submucosally infiltrating adenocarcinoma. J Clin Gastroente- rol 1997; 25: 678-81.
Korkmaz U, Erdoğmuş B, Akcan Y, et al. Gastrik inlet dokusunda rast- lantısal radyasyonun neden olduğu ciddi özofageal benign striktür. Tur- kiye Klinikleri J Gastroenterohepatol 2009; 16: 21-3
Leung WK, Siu KL, Kwok CK, et al. Isolation of Helicobacter pylori from vomitus in children and its implication in gastro-oral transmission. Am J Gastroenterol 1999; 94: 2881-4.
Alagözlü H, Şimşek Z, Ünal S, et al. Is there an association between He- licobacter pylori in the inlet patch and globus sensation? World J Gas- troenterol 2010; 16: 42-7.
Borhan-Manesh F, Farnum JB. Study of Helicobacter pylori colonization of patches of heterotopic gastric mucosa (HGM) at the upper esophagus. Dig Dis Sci 1993; 38: 142-6.
Avidan B, Sonnenberg A, Chejfec G, et al. Is there a link between cervi- cal inlet patch and Barrett's esophagus? Gastrointest Endosc 2001; 53: 717-21.
Galan AR, Katzka DA, Castell DO. Acid secretion from an esophageal in- let patch demonstrated by ambulatory pH monitoring. Gastroenterology 1998; 115: 1574-6.
Jabbari M, Goresky CA, Lough J, et al. The inlet patch: heterotopic gas- tric mucosa in the upper esophagus. Gastroenterology 1985; 89: 352-6.
Sperling RM, Grendell JH. Adenocarcinoma arising in an inlet patch of the esophagus. Am J Gastroenterol 1995; 90: 150-2.