Muhammet Yener AKPINAR, Metin UZMAN, Zeynep GÖKTAŞ, Gülçin Güler ŞİMŞEK, Evrim KAHRAMANOĞLU AKSOY, Ferdane SAPMAZ, Yaşar NAZLIGÜL

Kolorektal Kanserde Endoskopik Özelliklerler Tümör Patolojisini ve Tümör Evresini Predikte Edebilir mi?

Giriş ve Amaç: Kolorektal kanserli hastalarımızın demografik özelliklerini ve tanı anındaki endoskopik özelliklerinin kolorektal kanserin patolojik özellikleri ile olan ilişkisini incelemeyi hedefledik. Gereç ve Yöntem: Hastanemiz Endoskopi Ünitesinde Ocak 2010-Ekim 2017 tarihleri arasında kolonoskopi esnasında kolorektal kanser ön tanısı ile biyopsi alınan ve patolojileri kolorektal kanser gelen hastalar çalışmaya dahil edildi. Tümöre bağlı lüminal obstrüksiyon, tümörün makroskopik özellikleri gibi endoskopik özellikler ve kolorektal kanserin patolojik özellikleri retrospektif olarak incelendi. Bulgular: Çalışmamıza 168 hasta dahil edildi. Hastaların en sık başvuru şikayeti kabızlık olup kolonda kanserin en sık izlendiği yer sigmoid kolondu. Hematokezya sol kolon yerleşimli kanserlerde diğer bölgelerdekine göre anlamlı olarak daha sık izlendi (p=0.02). Cinsiyetler arasında başvuru şekli, kanser lokalizasyonu ve endoskopik obstrüksiyon farklılık göstermedi. Endoskopik obstrüksiyonu olan hastalarda kolorektal kanserin kötü diferansiasyonu anlamlı olarak daha fazlaydı (p=0.015). Sonuç: Endoskopun geçemeyeceği şekilde lüminal obstrüksiyonu olan hastaların yakından izlenmeleri, ameliyatlarının geciktirilmeden yapılması ve ameliyat sonrası daha kısa aralıklarla takibi bu hastaların sağkalımları üzerine etkili olabilir.

Anahtar Kelimeler:

Endoskopi, kanser diferansiasyonu, kolorektal kanser

Can the Endoscopic Features of Colorectal Carcinomas Predict Tumor Pathology and Stage?

Background and Aims: Our aim was to evaluate the demographic features of our colorectal cancer patients and assess the association between endoscopic and pathologic features in those patients. Materials and Methods: In this study, we retrospectively evaluated the medical records of patients who were diagnosed with colorectal cancer through biopsy taken by colonoscopy in the endoscopy unit of our hospital between January 2010 and October 2017. We analyzed endoscopic features of colorectal cancer such as luminal obstruction, macroscopic appearance, and histological features. Results: We obtained data from 168 patients for this study. The most common symptom was constipation and the most common cancer location was the sigmoid colon. Hematochezia was found to be significantly higher in cancers located in the left colon (p = 0.02). Symptoms, cancer location, and endoscopic obstruction were not significantly different between genders. Poor histological differentiation was significantly higher in the endoscopic obstruction group (p = 0.015). Conclusion: Immediate surgery and close follow-up in patients with endoscopic obstruction can impact their survival.

Keywords:

Colorectal cancer, cancer differentiation, endoscopy,

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