Adil COŞKUN, Serkan BORAZAN, Abdülvahit YÜKSELEN, İbrahim METEOĞLU, İmran KURT ÖMÜRLÜ, Mehmet Hadi YAŞA

Aydın bölgesindeki üst gastrointestinal sistem malignitelerinin özellikleri

Giriş ve Amaç: Üst gastrointestinal sistem maligniteleri tüm dünyada önemli mortalite ve morbidite nedenlerindendir. Tanıda özofagogastroduodenoskopi altın standart işlemdir. Çalışmadaki amacımız endoskopi ünitemizde özofagogastroduodenoskopi işlemi ile tespit ettiğimiz ve biyopsi ile de tanısı kesinleşen üst gastrointestinal sistem malignitelerinin yaş, cinsiyet, lokalizasyon ile histopatolojik tipleri ve işlem öncesi hasta semptomları gibi bazı özelliklerini belirlemekti. Gereç ve Yöntem: Endoskopi ünitemizde özofagogastroduodenoskopi yapılan 7.688 hastadan malignite saptanan 209 (%2,71) vaka çalışmaya alındı. Bulgular: Özofagogastroduodenoskopi işleminde malignite saptanan hastaların 145’i erkek (%69,4), 64’ü kadın (%30,6) olup yaş ortalaması 62,18±12,07 yıldı. Malignitelerin %21,1’i özofagusta, %75,1’i midede ve %3,8’i duodenumda saptandı. Yapılan histopatolojik incelemede, özofagus kanserlerinin %84,1’i squamöz hücreli karsinom, %15,9’u adenokarsinom; mide kanserlerinin %87,9’u adenokarsinom, %3,8’i malign epitelyal tümör, %5,8’i lenfoma, %2,5’i nöroendokrin tümör; duodenum kanserlerinin %87,5’i adenokarsinom, %12,5’i malign epitelyal tümör olarak tespit edildi. Sonuç: Üst gastrointestinal sistem maligniteleri en sık midede, 2. sıklıkta özofagusta saptanmaktadır. Nadirde olsa duodenumda tümör görülebilmektedir.

Anahtar Kelimeler:

Özofagogastroduodenoskopi, malignite

Features of upper gastrointestinal tract malignancies in Aydin region

Background and Aims: Upper gastrointestinal tract malignancies are among the major causes of morbidity and mortality worldwide. Esophagogastroduodenoscopy is the gold standard for the diagnosis of upper gastrointestinal tract cancers. The aim of our study was to determine features of upper gastrointestinal tract malignancies including age, gender, localization, histological types and symptoms prior to the procedure in the cases that were identified by in our endoscopy unit and finally diagnosed by biopsy. Materials and Methods: A total of 209 (2.71%) of 7.688 patients who underwent esophagogastroduodenoscopy in our endoscopy unit and who were diagnosed with malignancy were included in the study. Results: Of the patients diagnosed with malignancy by esophagogastroduodenoscopy, 145 were men (69,4%) and 64 were women (30,6%). Mean age was 62.18±12.07 years. In the sample, 21.1% of malignant tumors were detected in the esophagus, 75.1% in the stomach, and 3.8% in the duodenum. Histopathological examination showed that 84.1% of esophageal tumors were squamous cell carcinoma, and 15.9% were adenocarcinoma; 87.9% of gastric tumors were adenocarcinoma, 3.8% were malignant epithelial tumors, 5.8% were lymphoma, and 2.5% were neuroendocrine tumors; 87.5% of duodenal tumors were adenocarcinoma, and 12.5% were malignant epithelial tumors. Conclısions: Upper gastrointestinal tract malignancies are most common in the stomach, and the second most common organ is esophagus. Although rare, tumors can be seen in the duodenum.

Keywords:

Özofagogastroduodenoskopi, malignite,

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