Altmış yaş üstü erişkin hastalarda demir eksikliği anemisi nedeni olarak yalnız başına üst gastrointestinal sistem patolojilerinin katkısının araştırılması

Giriş ve Amaç: Demir eksikliği olan yaşlı popülasyonda üst gastrointestinal sistemin yalnız başına katkısını ve Helicobacter pylori ile olan ilişkinin belirlenmesi. Gereç ve Yöntem:Retrospektif kesitsel kohort düzeninde elektronik tıbbi kayıtların taranması ile demir eksikliği anemisi ile ilişkili diğer risk faktörlerinin elendiği ve alt gastrointestinal sistem taramalarının normal olduğu hastalar seçilmiştir. Bulgular:60 yaş üzerindeki yaşlı popülasyonda histopatolojik olarak 39 hastada Helicobacter pylori pozitifliği saptandı. Ayrıca mideden elde edilen biyopsilerde 41 hastada prekanseröz lezyon ve 3 hastada da mide kanseri saptandı. Özofagus ve duodenum incelemesinde 1 hastada Çölyak hastalığı saptandı. Helicobacter pylori pozitif olan hastalarda olmayanlara göre hemoglobin seviyesinde farklılık saptanmadı ancak pozitif gruptaki hastaların daha genç ve daha çok ferritin düşüklüğü olduğu bulundu. Sonuç:Yaşlı hasta grubunda demir eksikliği anemisinde diğer etkenler normal olsa bile üst gastrointestinal taranması yüksek riskli lezyonlar, malignite ve Helicobacter pylori ile olan ilişkisi nedeni ile gereklidir.

The contribution of upper gastrointestinal system pathology to iron deficiency anemia in an adult population over 60 years of age

Background and Aims:In an elderly patient population, we aimed to define the contribution of upper gastrointestinal system pathology (malignancies, high-risk precancerous lesions, Helicobacter pylori) to iron deficiency anemia. Materials and Methods:A retrospective cohort study was designed to define the contribution of upper gastrointestinal system pathology to iron deficiency anemia. Electronic hospital records formed of standard medical terminology constituted the basis of data extraction. Based on the exclusion criteria, only patients with possible upper gastrointestinal system pathology were evaluated. Results:In 39 patients, H. pylori-related pathology was found, whereas 41 patients had presented with a high-risk lesion of the stomach. Three patients were found to have gastric cancer and 1 patient had been diagnosed with Celiac disease. Age and ferritin levels were lower in patients with H. pylori positivity. Conclusions:In this elderly patient population, the contribution of upper gastrointestinal system pathology (high-risk lesions, overt malignancy, H. pylori association) to iron deficiency anemia is important, and H. pylori is a treatable cause of iron deficiency anemia.

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