INVESTIGATION OF SINGLE STRANDED DNA -MAGNETIC NANOPARTICLE INTERACTION BY MAGNETO-OPTICAL LINEAR DICHROISM

INVESTIGATION OF SINGLE STRANDED DNA -MAGNETIC NANOPARTICLE INTERACTION BY MAGNETO-OPTICAL LINEAR DICHROISM

In this study, interaction of produced magnetic fluid with single stranded DNA was investigated by using designed magneto-optical linear dichroism (MOLD) measurement system. Fe3O4 nanoparticles, produced by using co-precipitation method were characterized by means of structure, magnetic, and size distribution. These nanoparticles coated with oleic acid and Tetramethylammonium (TMA) in water and ethanol. Change of the linear dichroism property of fluid under applied magnetic field was observed due to the interaction of produced magnetic fluid with single stranded DNA. Obtained results were shown that it is possible to develop a single stranded DNA sensor by using its interaction with magnetic liquid and MOLD effect. 

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  • [1] Hernandez , R. E., Baeza , A., & Regi , M. V., “Smart Drug Delivery through DNA/Magnetic Nanoparticle Gates.” ACS Nano, s.1259-1264. 2011.
  • [2] Pooja, M. T., Komal, V., Vida, A. D., & Shree, R. S. “Functionalized Gold Nanoparticles and Their Biomedical Applications.” Nanomaterials, s.31-63 ,2011. 33333
  • [3] Melancon, M., & Lu, W. “Gold-Based Magneto-Optic Nanostructures: Challenges for In Vivo Applications in Cancer Diagnostics and Therapy.” Mater Res. Bull, s.415-421 ,2009
  • [4] Xu, M., and Ridler, P. J., 1997, Linear dichroism and birefringence effects in magnetic fluids, American Institute of Physics.
  • [5] Cao, S. W., Zhu, Y. J., & Chang, J. “Fe3O4 polyhedral nanoparticles with a high magnetization synthesized in mixed solvent ethylene glycol–water system.” New J. Chem., s.1526–1530 ,2008
  • [6] Xu, M., & Ridler, P. J., “Linear dichroism and birefringence effects in magnetic fluids.” American Institute of Physics. ,1997