Diyabetik gebelerde glikolize hemoglobin A1c (HbA1c) düzeyi ile gebelik komplikasyonları arasındaki ilişki-Retrospektif vaka-kontrol çalışması

Amaç: Diabetes mellitus (DM) tanılı gebelerde glikolize hemoglobin A1C (HbA1c) düzeyleri ile gebelikte meydana gelebilecek olan komplikasyonlar arasında ilişki olup olmadığını saptamak. Gereç ve Yöntemler: Çalışmamız retrospektif vaka-kontrol çalışmasıdır. Ocak 2013 ve Aralık 2017 tarihleri arasında Aydın Adnan Menderes Üniversitesi hastanesinde yapılmıştır. Çalışmamız 321 hasta üzerinde yapılmıştır. Hastalarda HbA1C düzeyine göre komplikasyon oranlarına bakılmıştır. Bulgular: HbA1c değerleri 66 gebede %4-5.9, 157 gebede %6-7.9 ve 91 gebede HbA1c≥%8’dir. Pregestasyonel DM tanılı gebelerde gestasyonel diabetes mellitus (GDM) tanılı gebelere kıyasla preeklampsi, fetal distres, preterm doğum, omuz distosisi ve yenidoğan hipoglisemisi daha sık saptanmıştır (p%6 ve HbA1c %5-5.9 olan gebelerde HbA1c %4-4.9 arasında olan gebelere kıyasla GHT, preeklampsi, EDT, polihidroamnios, small for gestational age (SGA), LGA, fetal distres, preterm doğum, yenidoğan hipoglisemisi ve yenidoğan solunum sıkıntısı daha sık saptanmıştır (p

Anahtar Kelimeler:

Glikolize hemoglobin A1c (HbA1c), Gebelik Komplikasyonu, Gestasyonel Diabetes Mellitus, Diyabette Gebelik

The relationship between glycosylated hemoglobin A1c (HbA1c) levels and pregnancy complications in a diabetic pregnant women-Retrospective case-control study

Aim: To determine whether there is a relationship between glycosylated hemoglobin A1C (HbA1c) levels and complications that may occur during pregnancy in pregnant women with diabetes mellitus (DM). Material-Methods: Our study is a retrospective case-control study. It was carried out in Aydın Adnan Menderes University hospital between January 2013 and December 2017. It was performed on 321 patients. Results: HbA1c values were pregnant women's 4-5.9% in 66 , 6-7.9% in 157 HbA1c≥8% in 91. Compared to gestational diabetes mellitus (GDM), preeclampsia, fetal distress, preterm delivery, shoulder dystocia, and neonatal hypoglycemia were found more frequently in pregnant women with pregestational DM (p6% and HbA1c between 5-5.9%, GHT, preeclampsia, TPL, polyhydramnios, small for gestational age (SGA), LGA, fetal distress, preterm birth, neonatal hypoglycemia, and neonatal respiratory distress were found more frequently compared to pregnants with 4-4.9% HbA1c. Conclusion: Obstetric complication rates increased in pregnant women with pregestational DM, Type 1 DM, GDMA2 and high HbA1c values.

Keywords:

Glycolyzed Hemoglobin A1c (HbA1c), Pregnancy Complication, Gestational Diabetes Mellitus, Pregnancy in Diabetes,

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ISSN: 2636-851X
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 2018
Yayıncı: Uşak Cerrahi Derneği

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