Elastic Characteristics of The Aorta in Patients with A New Diagnosis of Metabolic Syndrome

Metabolic syndrome (MS) is a known risk factor of cardiovascular disease. However, it is not identified whether MS made alterationsin the elasticity of the aorta in the early period before significant atherosclerosis occurred. The purpose of the study was to evaluateaortic elastic properties of patients who were newly diagnosed with MS.The research was performed among 100 patients of newly diagnosed MS (49 males; mean age 46 ± 9 years) with normal sinusrhythm, and 55 cases without MS (29 males; mean age 45 ± 9 years), matched by age . All participants underwent comprehensivephysical and cardiological examination, biochemical examination, anthropological measurement and echocardiography.Aortic diameter change was significantly lower in MS group compared to control group (0.014 ± 0.04 vs 0.25 ± 0.1, p

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1. Wilson PWF, Kannel WB, Silbershatz H, D’Agostino RB. Clustering of metabolic factors and coronary heart disease. Arch Intern Med 1999; 159: 1104-1109.

2. Grundy SM. Hypertriglyceridemia, insulin resistance, and the metabolic syndrome. Am J Cardiol 1999; 83: 25F-29F.

3. Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle aged men. JAMA 2002; 288: 2709-2716.

4. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of Cardiovascular Events and AllCause Mortality With Arterial Stiffness. J Am Coll Cardiol 2010; 55: 1318-1327.

5. Bonarjee VVS. Arterial Stiffness: A Prognostic Marker in Coronary Heart Disease. Available Methods and Clinical Application. Front Cardiovasc Med 2018; 5: 64.

6. Lacombe F, Dart A, Dewar E, Jennings G, Cameron J, Laufer E. Arterial elastic properties in man: a comparison of echoDoppler indices of aortic stifnes. Eur Heart J 1992; 13: 1040-1045.

7. Stefanadis C, Stratos C, Boudoulas H, Kourouklis C, Toutouzas P. Distensibility of the ascending aorta: comparison of invasive and non-invasive techniques in healthy men and in men with coronary artery disease. Eur Heart J 1990; 11: 990-996.

8. Vitarelli A, Giordano M, Germanò G, Pergolini M, Cicconetti P, Tomei F, et al. Assessment of ascending aorta wall stiffness in hypertensive patients by tissue Doppler imaging and strain Doppler echocardiography. Heart 2010; 96: 1469-1474.

9. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: Findings from the third National Health and Nutrition Examination Survey. JAMA 2002; 287: 3569.

10. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 2015; 28: 1-39.e14.

11. Nemes A, Geleijnse ML, Forster T, Soliman OI, Ten Cate FJ, Csanády M. Echocardiographic evaluation and clinical implications of aortic stiffness and coronary flow reserve and their relation. Clin Cardiol 2008; 31: 304-309.

12. Brooks BA, Mdyneaux LM, Yue DK. Augmentation of central arterial pressure in Type 2 diyabetes. Diyabet Med 2001; 18: 374- 380.

13. Sutton–Tyrrell K, Newman A, Simonsick EM, Havlik R, Pahor M, Lakatta E, et al. Arterial stiffness and its association with clustering of metabolic syndrome risk factors. Diabetol Metab Syndr 2017; 9: 87.

14. Kalçık M, Yetim M, Doğan T, Doğan İ, Eser B, Bekar L, et al. Comparison of aortic pressures and aortic elastic properties between patients with end-stage renal disease and healthy controls. Interv Med App Sci 2019; 11: 77-83.

15. Franklin SS, Khan SA, Wong ND, Larson MG, Levy D. Is pulse pressure useful in predicting risk for coronary heart disease? The Framingham Heart Study. Circulation 1999; 100: 354-360.

16. Feistritzer HJ, Klug G, Reinstadler SJ, Reindl M, Niess L, Nalbach T, et al. Prognostic Value of Aortic Stiffness in Patients After STElevation Myocardial Infarction. J Am Heart Assoc 2017; 6: e005590.

17. Nakanishi N, Suzuki K, Tatara K. Clustered features of the MS and the risk for increased aortic pulse wave velocity in middle-aged Japanese men. Angiology 2003; 54: 551-559.

18. Kass DA. Ventricular arterial stiffening: integrating the pathophysiology. Hypertension 2005; 46: 185-193.

19. Kangas P, Tikkakoski AJ, Tahvanainen AM, Leskinen MH, Viitala JM, Kahonen M, et al. Metabolic syndrome may be associated with increased arterial stiffness even in the absence of hypertension: a study in 84 cases and 82 controls. Metabolism 2013; 62: 1114-1122.

20. Ciccone M, Vettor R, Pannacciullli N, Minenna A, Bellacicco M, Rizzon P, et al. Plasma leptin is independently associated with intima-media thickness of the common carotid artery. Int J Obes Relat Metab Disord 2001; 25: 805-810.

21. Singhal A, Farooqi IS, Cole TJ, O’Rahilly S, Fewtrell M, Kattenhorn M, et al. Influence of leptin on arterial distensibility: a novel link between obesity and cardovascular disease? Circulation 2002; 106: 1919-1924.

22. Schillaci G, Pirro M, Vaudo G, Mannarino MR, Savarese G, Pucci G, et al. Metabolic syndrome is associated with aortic stiffness in untreated essential hypertension. Hypertension 2005; 45: 1078-1082.
Eastern Journal of Medicine-Cover
  • ISSN: 1301-0883
  • Başlangıç: 1996
  • Yayıncı: ERBİL KARAMAN
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