The Clinical Effect of Platelet-Rich Plasma Injections On Symptomatic Meniscal Tears of The Knee

This study aims to assess the clinical efficacy of intra -articular platelet-rich plasma injections in symptomatic meniscustears of the knee.Forty one patients (12 males, 29 females; mean age 38.2±8.37 years; range 21 to 50 years) with meniscal tear included inthe study. Lateral patellofemoral approach was used for intra-articular platelet-rich plasma injections. The platelet-richplasma applications were performed three times one week apart. Patients were evaluated usingVisual Analogue Scale (VAS)and Lequesne Index. Baseline scores were obtained pre -first injection and compared to satisfaction scores one- and fourweeks post-last injections.Compared with pre-treatment, at post-treatment weeks 1 and 4, both VAS and Lequesne Index scores significantlydecreased (p

___

1. Makris EA, Hadidi P, Athanasiou KA. The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration. Biomaterials 2011; 32: 7411-7431.

2. Rao AJ, Erickson BJ, Cvetanovich GL, Yanke AB, Bach BR Jr, Cole BJ. The meniscus-deficient knee biomechanics, evaluation, and treatment options. Orthop J Sports Med 2015; 3: 2325967115611386.

3. Beaufils P, Becker R, Kopf S, Matthieu O, Pujol N. The knee meniscus: management of traumatic tears and degenerative lesions. EFORT Open Rev 2017; 2: 195-203.

4. Doral MN, Bilge O, Huri G, Turhan E, Verdonk R. Modern treatment of meniscal tears. EFORT Open Rev 2018; 3: 260-268.

5. Le ADK, Enweze L, DeBaun MR, Dragoo JL. Current Clinical Recommendations for Use of Platelet-Rich Plasma. Curr Rev Musculoskelet Med 2018; 11: 624-634.

6. Wasserman A, Matthewson G, MacDonald P. Platelet-Rich Plasma and the KneeApplications in Orthopedic Surgery. Curr Rev Musculoskelet Med 2018; 11: 607-615.

7. Dawood AS, Salem HA. Current clinical applications of platelet-rich plasma in various gynecological disorders: An appraisal of theory and practice. Clin Exp Reprod Med 2018; 45: 67-74.

8. Stoller DW. Magnetic Resonance Imaging in Orthopaedicsand Sports Medicine. 3rd edition. Philadelphia: Lippincott Williams &Wilkins; 2007. pp. 306-405.

9. Basaran S, Guzel R, Seydaoglu G, GulerUysal F. Validity, reliability, and comparison of the WOMAC osteoarthritis index and Lequesne algofunctional index in Turkish patients with hip or knee osteoarthritis. Clin Rheumatol 2010; 29: 749-756.

10. Moatshe G, Morris ER, Cinque ME, et al. Biological treatment of the knee with plateletrich plasma or bone marrow aspirate concentrates. Acta Orthop 2017; 88: 670-674.

11. Dhurat R, Sukesh M. Principles and Methods of Preparation of Platelet-Rich Plasma: A Review and Author's Perspective. J Cutan Aesthet Surg 2014; 7: 189-197.

12. Kaleka CC, Debieux P, da Costa Astur D, Arliani GG, Cohen M. Updates in biological therapies for knee injuries: menisci. Curr Rev Musculoskelet Med 2014; 7: 247-255.

13. Cengiz IF, Pereira H, Espregueira-Mendes J, Reis RL, Oliveira JM. The Clinical Use of Biologics in the Knee Lesions: Does the Patient Benefit? Curr Rev Musculoskelet Med 2019; 406-414.

14. Huang G, Hua S, Yang T, Ma J, Yu W, Chen X. Platelet-rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors. Exp Ther Med 2018; 15: 3096-3102.

15. Steineman BD, LaPrade RF, Santangelo KS, Warner BT, Goodrich LR, Haut Donahue TL. Early Osteoarthritis After Untreated Anterior Meniscal Root Tears: An In Vivo Animal Study. Orthop J Sports Med 2017; 5: 2325967117702452.

16. Englund M, Guermazi A, Gale D, et al. Incidental meniscal findings on knee MRI in middle-aged and elderly persons. N Engl J Med 2008; 359: 1108-1115.

17. Figueroa D, Figueroa F, Calvo R, Vaisman A, Ahumada X, Arellano S. Platelet-rich plasma use in anterior cruciate ligament surgery: systematic review of the literature. Arthroscopy 2015; 31: 981-988.

18. Cook CS, Smith PA. Clinical Update: Why PRP Should Be Your First Choice for Injection Therapy in Treating Osteoarthritis of the Knee. Curr Rev Musculoskelet Med 2018; 11: 583-592.
Eastern Journal of Medicine-Cover
  • ISSN: 1301-0883
  • Başlangıç: 1996
  • Yayıncı: ERBİL KARAMAN
Sayıdaki Diğer Makaleler

Reliability of Youtube Videos On Knee Joint Injection

Sezai ÖZKAN, Cihan ADANAŞ, Şeyhmus KAPLAN, Volkan ŞAH

Radiological Imaging Findings of Avalanche Victims With Traumatic Lesions In Van Eastern Province of Turkey

Sercan ÖZKAÇMAZ, İlyas Dündar, Leyla Turgut ÇOBAN, Fatma DURMAZ, Iskan ÇALLI, İbrahim İLİK

Abnormal First and Second Trimester Maternal Serum Marker Levels For Aneuploidy Screening and Adverse Pregnancy Outcomes

Lale SUSAN KARAKIŞ, Engin TURKGELDİ, Hüseyin KIYAK, Neşe YÜCEL

Examining of The Individuals Who Have Attempted Suicide In The East of Turkey In Terms of Psychological Factors

Faruk KURUHAN, Gülsüm Zuhal KAMİŞ, Abdullah ATLI

Elastic Characteristics of The Aorta in Patients with A New Diagnosis of Metabolic Syndrome

Ender Özgün ÇAKMAK, Ali KARAGÖZ, Ugur FİNDİKÇİOĞLU, Emrah ERDOĞAN, Ertuğrul ZENCİRCİ, Fatma Seden ERTEN ÇELİK, Özer SOYLU

The Effect of Infliximab on Oxidative Stress in Ovarian Tissue of the Rat with Ovarian Hyperstimulation Syndrome

Deniz DİRİK, Ahmet Ufuk KÖMÜROĞLU

Outcomes of The Modified Mcbride Procedure For Hallux Valgus: Analysis of The Radiographic Measurements

Emre BİLGİN

Perineal Color Doppler Ultrasound of Periurethral Vascularization In Women Affected By Urinary Stress Incontinence

Sara MASCARETTİ, Carlo MASCİOCCHİ, Giulio MASCARETTİ, Eva FASCETTİ, Angela DALFONSO, Alessandro SERVA, Pietro CİGNİNİ, Michele FICHERA

Serum Ionized Calcium Levels May Be More Closely Related To The Admission Qtc Interval Than Total Calcium Levels In Patients Hospitalized With Covid-19

Murat ÇAP, Ferhat IŞIK, Önder BİLGE, Bernas ALTINTAŞ, Abdurrahman AKYÜZ, Burhan ARSLAN, Ümit İNCİ, Rojhat ALTINDAĞ, İlyas KAYA, Flora OZKALAYCI, İbrahim Halil TANBOĞA, Kemal GÜNEŞ

Endoscopic and Histopathological Findings, and The Presence of Helicobacter Pylori in Diabetic and NonDiabetic Patients Admitted to the Emergency Department with Dyspeptic Complaints

Mehmet Ali BİLGİLİ