Assessment of Sleep Quality in Patients with Type 2 Diabetes Mellitus: A Case-control Study

Sleep disorders increase risk for impaired glucose tolerance, insulin resistance, and type2 diabetes mellitus through changes in hormone release involved in energy homeostasis; on the other hand, complications occurring in patients with type 2 diabetes mellitus also lead sleep disorders. In the present study, it was aimed to assess sleep quality in patients with type 2 diabetes mellitus.The study included 40 patients (aged 18-65 years) diagnosed as type 2 diabetes mellitus (21 women; 19 men) and 42 healthy controls (26 women; 16 men). The data were collected using demographic data sheet, Pittsburgh Sleep Quality Index (PSQI) in this case-control study.In patients with type 2 diabetes mellitus, total PSQI score and component scores for sleep duration, sleep disturbance, use of sleep medication and daytime dysfunction were significantly higher when compared tocontrols. In addition, the proportion of patients with poor sleep quality was significantly higher in the patients with type 2 diabetes mellitus compared to controls (82.5% vs. 59.5%; 2= 5.224, p=0.022). The age and body mass indexwere higher in patients with type 2 diabetes mellitus compared to controls. It was found that sleep quality was poorer in patients with type 2 diabetes mellitus. It is important to identify problems that may result from sleep disorders and adverse effects of type 2 diabetes mellitus on sleep quality. To achieve glucose control in patients with type 2 diabetes mellitus, it is essential to improve sleep quality in addition to current approachesused in clinical practice.

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1. Van Cauter E, Knutson K, Leproult R, Spiegel K. The impact of sleep deprivation on hormones and metabolism. Medscape Neurology 2005; 7:1.

2. Talaz D, Kızılcı S. Tip 2 Diyabet Riski ve Hastalık Sürecinde Uykunun Rolü Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi 2015; 8: 203-208.

3. West SD, Nicall DC, Stradling JR. Prevalence of obstructive sleep apnoea in men with type 2 diabetes. Thorax 2006; 61: 945-950.

4. Björkelund C, Carlson DB, Lapidus L, Lissner L, Månsson J, Skoog I and Bengtsson C. Sleep disturbances in midlife unrelated to 32-year diabetes ıncidence. Diabetes Care 2005; 28: 2739-2744.

5. Lívia A. Lopes, Camila de MM Lins, Vanessa G. Adeodato Diana P. Quental, Pedro FC de Bruin, Renan M. Montenegro Jr. Restless legs syndrome and quality of sleep in type 2 diabetes. Diabetes Care 2005; 28: 2633-2636.

6. Mallon L, Broman JE, Hetta J. High ıncidence of diabetes in men with sleep complaints or short sleep duration. Diabetes Care 2005; 28: 2762-2767.

7. Kessler L, Nedeltcheva A, Imperial J, Penev PD. Changes in serum TSH and free T4 during human sleep restriction. Sleep 2010; 33: 1115-1118.

8. Somers VK, Dyken ME, Clary MP, Abboud, FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995; 96: 1897-904.

9. Van Cauter E, Holmback U, Knutson K, Leproult R, Miller A, Nedeltcheva A, Silvana Pannain S, P Penev, Tasali E and Spiegel K. Impact of sleep and sleep loss on neuroendocrine and metabolic function. Horm Res 2007; 67: 2-9.

10. Van Cauter E, Spiegel K, Tasali E, Leproult R. Metabolic consequences of sleep and sleep loss. Sleep Med 2008; 9: 23-28.

11. Copinschi G, Leproult R, Spiegel K. The important role of sleep in metabolism. Front Horm Res 2014; 42: 59-72.

12. Reutrakul S, Van Cauter E. Interactions between sleep, circadian function, and glucose metabolism: implications for risk and severity of diabetes. Ann. N.Y. Acad. Sci 2014; 1311: 151-173.

13. Tare A, Lane JM, Cade B E, Grant SFA, Hsu Chen T, Punjabi NM Lauderdale D S , Zee P C , Gharib S A, Gottlieb D J, Scheer Frank A J L , Redline S and Saxena R. Sleep duration does not mediate or modify Association of common genetic variants with type 2 diabetes. Diabetologia 2014; 57:339–346.

14. Pyykkönen A J, Isomaa B, Pesonen AK, Eriksson JG, Groop L, Tuomi T, Räikkönen K. Sleep duration and insulin resistance in individuals without type 2 diabetes: The ppp botnia study. Ann Med 2014; 46: 324-329.

15. Davies SK, Ang JE, Revell VL, Holmes B, Mann A, Robertson FP, Cui N, Middleton B, Ackermann K, Kayser M, Thumser AE, Raynaud FI and Skene DJ. Effect of sleep deprivation on the human metabolome. Proc Natl Acad Sci U S A 22; 2014; 111: 10761-10766.

16. Öztürk M. Hastanede Yatan Yetişkin Hastaların Uygu Gereksinimlerini Etkileyen Faktörlerin İncelenmesi. Çukurova Üniversitesi Sağlık Bilimleri Enstitüsü Yüksek Lisans Tezi, 2003, Adana.

17. Hood, MM, Reutrakul S, Crowley SJ. Nighteating in patients with type 2diabetes. Associations with glycemic control, eating patterns, sleep, and mood. Appetite 2014; 79: 91-96.

18. Kurose T, Hyo T, Yabe D, Seino Y. The role of chronobiology and circadian rhythms in type 2 diabetes mellitus: implications for management of diabetes. ChronoPhysiology and Therapy 2014; 4: 41-49.

19. WHO. Obesity: Preventing and Managing the Global Epidemic: Report of a WHO Consultation on Obesity. Geneva, Switzerland: WHO; 2000. WHO Technical report Series 894.

20. Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 1989; 28: 193-213.

21. Ağargün MY, Kara H, Anlar Ö. The Validity and Reliability of the Pittsburgh Sleep Quality Index. Türk Psikiyatr Derg 1996; 7: 107-115.

22. Güneş Z, Körükcü Ö, Özdemir G. Diyabetli Hastalarda Uyku Kalitesinin Belirlenmesi Atatürk Üniversitesi Hemşirelik Yüksekokulu Dergisi 2009; 12: 10-17.

23. Uran G. Kırsal Kesimde Evde Ve Huzurevlerinde Kalan 60 Yaş Üzeri Yaşlılarda Pittsburg Uyku Kalitesi İndeksi İle Uyku Kalitelerinin Karşılaştırılması. Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Yüksek Lisans Tezi, 2001, Ankara.

24. Curt L. Rohlfing, Hsiao-Mei Wiedmeyer, Randie R. Little, Jack D. England, Alethea Tennill and David E. Goldstein. Analysis of glucose profiles and HbA1c in the Diabetes Control and Complications Trial Diabetes Control and Complication, Diabetes Care 2002; 25: 275-278.

25. Khan SE, Hull RL, Utzschinder KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006; 444: 840-846.

26. Fiorentini A, Valente R, Perciaccante A, Tubani L. Sleep’s quality disorders in patients with hypertension and type 2 diabetes mellitus. International Journal of Cardiology 2007; 114: 50-52.

27. Yüksel S. Tip 1 Ve Tip 2 Diyabetik Hastaların Uyku Kalitesi, Anksiyete, Depresyon Ve Yaşam Kalitesinin Değerlendirilmesi. Afyonkarahisar Kocatepe Üniversitesi Sağlık Bilimleri Enstitüsü Yüksek Lisans Tezi, 2007, Afyonkarahisar.

28. Sridhar GR, Madhu K. Prevalence of sleep disturbances in diabetes mellitus. Diab Res Clin Practice 1994; 23: 183-186.

29. Einhorn D, Stewart DA, Erman MK, Gordon N, Athena Philis-Tsimikas A and Casal E. Prevalence apnea in a population of adults with type 2 diabetes mellitus. Endocrin Practice 2007; 13: 355-362.

30. Sukegawa T, Itoga M, Seno H, Miura S, Inagaki T, Saito W and et al. Sleep disturbances and depression in the elderly in Japan. Psychiatry and Clinical Neurosciences 2003; 57: 265-270.

31. Williams JR. Gerontologic nurse practitioner care guidelines: sleep management in elderly patients. Geriatric Nursing 2004; 25: 310-312.

32. Gökçe S. Kalp yetmezliği olan hastaların uyku kalitesinin ve etkileyen etmenlerin incelenmesi. Hemşirelik Programı Yayınlanmamış Yüksek Lisans Tezi, Dokuz Eylül Üniversitesi Sağlık Bilimleri Enstitüsü. 2008, İzmir.

33. Altın M. Erciyes Üniversitesi Araştırma Görevlilerinde Uyku Sorunları ve Uyku Kalitesinin Değerlendirilmesi. Yayınlanmamış Tez, Erciyes Üniversitesi Tıp Fakültesi Halk Sağlığı Anabilim Dalı. 2011, Kayseri.

34. Göktaş E, Çelik F, Özer H, Çıray Gündüzoğlu N. Obez Bireylerin Uyku Kalitesinin Belirlenmesi. Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi 2015; 8: 156-161.

35. Aslan B. Tip 1 Diyabetli Adölesan Bireylerde Uyku Kalitesi Ve Beslenme Durumu Arasındaki İlişkinin Belirlenmesi. Başkent Üniversitesi Sağlık Bilimleri Enstitüsü Beslenme Ve Diyetetik Anabilim Dalı Yüksek Lisans Tezi, 2019, Ankara.

36. Von Schnurbein J, Boettcher C, Brandt S. Sleep and glycemic control in adolescents with type 1 diabetes. Pediatr Diabetes 2018; 19: 143-149.

37. Adler A, Gavan MY, Tauman R. Do children, adolescents, and young adults with type 1 iabetes have increased prevalence of sleep disorders? Pediatr Diabetes 2017; 18: 450-458.

38. Rajendran A, Parthsarathy S, Tamilselvan B, Seshadri KG, Shuaib M. Prevalence and correlates of disordered sleep in Southeast Asian İndians with type 2 diabetes. Diabetes & Metabolism Journal 2012; 36: 70-76.

39. Akça D. Tip 2 Diyabetli Hastalarda Diyabet Belirtilerinin Uyku Kalitesine Etkisi. İnönü Üniversitesi Hemşirelik Anabilim Dalı İç Hastalıkları Hemşireliği Programı Yüksek Lisans Tezi, 2016 Malatya.
Eastern Journal of Medicine-Cover
  • ISSN: 1301-0883
  • Başlangıç: 1996
  • Yayıncı: ERBİL KARAMAN
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