Mehmet Faruk GEYİK, Ertuğrul GÜÇLÜ

Kronik Hepatit B Tedavisine Güncel Yaklaşım

Kronik hepatit B (KHB) karaciğer sirozu, karaciğer yetmezliği ve hepatosellüler kanser gibihayatı tehdit eden komplikasyonlara neden olabilen ciddi bir enfeksiyon hastalığıdır. KHBtedavisinin ana hedefi bu komplikasyonların önlenmesi ve viral yükün azaltılmasıdır çünkümevcut antiviral tedaviler, Hepatit B virüs enfeksiyonunu tamamen temizlemekte yetersizdir.Bu makalede KHB’de uygulanan antiviral tedavinin güncel durumu ve antiviral ilaçlarözetlenmiştir

Anahtar Kelimeler:

Kronik hepatit B, Antiviral tedavi, Pegile interferon

Current Approach To Chronic Hepatitis B Therapy

Chronic hepatitis B (CHB) is a serious infectious diseases, leading to life threateningcomplications such as liver cirrhosis, hepatic decompensation and hepatocelluler carcinoma.The main goal for treatment of CHB is to prevent these complications, and to reduce the viralload, because current antiviral therapies are inadequate to eradicate Hepatitis B virus infection.In this article, current state of antiviral therapy of CHB and antiviral drugs were summarized

Keywords:

Chronic hepatitis B, Antiviral therapy, Pegylated interferon,

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