Fibromiyalji Sendromunda Kardiyovasküler Sistemin Değerlendirilmesi: Doku Doppler Ekokardiyografik İnceleme

Amaç: Biz Fibromiyalji (FM) hastalarında kardiyak yapı ve fonksiyonların hem geleneksel hemde yeni ve faydalı bir metot olan doku Doppler ekokardiyografik (DDE) yöntemle incelemeyiamaçladık. Ayrıca, hastalığın patogenezinde olası mekanizmalardan biri olarak gösterilenotonom fonksiyon bozukluğunu elektrokardiyografik olarak QT parametrelerini (QT maksimum,QT minimum ve QT dispersiyonu) ölçerek değerlendirdik. Yöntem: Çalışma aynı kliniğe başvuran 42 hasta (ortalama yaş 41, 38 kadın ) ve kontrol grubuolarak alınan tamamen sağlıklı 38 kişi üzerinde yapıldı. Bireylerin her birine tam bir fizikmuayene, elektrokardiyografik (50 mm/s hızla kaydedilen) ve ekokardiyografik (hemgeleneksel, hem de DDE) ile değerlendirme yapıldı.Bulgular: Elektrokardiografik kayıtların analizinde QT dispersiyonunda hafif fakat istatistikselolarak anlamlı olmayan bir artış saptandı. Geleneksel ekokardiyografik parametreler açısındanhasta grubu ile kontrol grubu benzerdi. Bununla birlikte bu çalışmanın önemli bir bulgusu hastagrubunda DDE yöntemi ile saptanan gevşeme bozukluğu idi. Em dalga hızı ve Em/Am oranlarıFM hastalarında kontrollere kıyasla anlamlı düzeyde düşüktü (sırasıyla, p < 0.005, p < 0.01).Sm ve Am dalga hızları ise her iki grupta da benzerdi. Sonuç: Bu çalışmada hasta grubunda DDE yöntemi ile saptanan sol ventrikülün gevşemebozukluğu FM’de görülen yorgunluk ve nefes darlığı gibi bazı semptomları kısmen açıklayabilir.Ayrıca tam bir kardiyak değerlendirme yapılması ile fibromiyaljinin patogenezindeki otonomikdisfonksiyon teorisini destekleyecek bulgular elde edilebilir

Anahtar Kelimeler:

Fibromiyalji, QT dispersiyonu, ekokardiyografi

Evaluation of Cardiovascular System in Fibromyalgia Syndrome: Tissue Doppler Echocardiographic Investigation

Aim: We aim to investigate besides the cardiac structures and functions by both conventionalmethods and Tissue Doppler Echocardiography (TDE) which is a new and useful method inpatients with Fibromyalgia (FM). Additionally, we evaluated QT parameters (QT maximum,QT minimum and QT dispertion) with the use of electrocardiography in order to measure theautonomic dysfunction which is a possible mechanism in the pathogenesis of the disease. Methods: The study was performed on 42 patients (mean age 41 years, 38 female) and 38completely healthy subjects (35 female, mean age of 42 years) who were admitted to the sameclinic were collected as the control group. All the individuals were undergone a completephysical examination, electrocardiography (recordings were displayed at 50 mm/s speed) andechocardiography evaluation (both conventional methods and TDE).Results: Analysis of electrocardiographic recordings revealed mildly increased mean QTdispertion in the patient group, but this difference was statistically insignificant. Analysis ofconventional echocardiographic parameters revealed similar results between the patient groupand the control cases. However, an important finding of this study is that significant diastolicdysfunction was found in the patient group which was recorded with the TDE technique. Emwave velocity and Em/Am ratios were significantly lower in patients with FM compared withcontrols (p

Keywords:

Fibromyalgia, QT dispertion, echocardiography,

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