Solunum Cihazına Bağlı Pnömonili Hastalarda Soluk Havasındaki Nitrik Oksit ve Hidrojen Peroksitin Tanısal Değerleri

Serbest radikallerin özellikle nitrik oksitin (NO), akciğer hastalıklarının takibinde önemi giderek artmaktadır. Çalışmada, hasta için herhangi bir risk taşımayan, örneklemesi kolay bir yöntemle, enflamatuvar parametrelerin ölçülmesi planlandı. Solunum cihazına bağlı 37 olgu alındı ( 27 hasta, 10 kontrol). Olguların birinci ve üçüncü günlerde soluk hava yoğunlaştırıcısı ile ekspiryum hava numunesi alınarak, NO, hidrojen peroksit (H2O2) ayrıca serumdan C-reaktif protein (CRP) düzeyleri ölçüldü. Birinci gün; pnömoni grubunun NO düzeyi kontrol grubundan istatistiksel olarak daha yüksekti (p 0,05). Pnömoni grubunun birinci ve üçüncü gün arasındaki NO düzeyindeki düşüş istatistiksel olarak anlamlı bulundu. (p

Dıagnostıc Values of Nıtrıc Oxıde and Hydrogen Peroxıde Content ın Inspıred Aır ın Patıents wıth Pneumonıa Under Respıratory Device

Free radicals, especially nitric oxide (NO), are of increasing importance in the management of lung diseases. In this study, we aimed to measure the inflammatory parameters with a method that is easy to sample and does not carry any risk to the patient. 37 cases connected to ventilator were included (27 patients, 10 controls). The first day and the third day, expiratory air was removed with an exhaled breath condenser and NO, hydrogen peroxide (H2O2) and serum C-reactive protein (CRP) were examined. First day; The NO level of the pneumonia group was statistically higher than the control group (p 0,05).The decrease in NO level between the first and third days of the pneumonia group was found to be statistically significant. (p

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