Ülkü KÜÇÜK, Sümeyye EKMEKÇİ, İbrahim ÇUKUROVA

Maksiller Sinüsün Psammom Cisminden Zengin Asinik Hücreli Karsinomu

Asinik hücreli karsinom (AHK) nadir görülen, yavaş büyüme hızına sahip, düşük dereceli malign tükürük bezi neoplazisidir. Tümör en sık parotiste saptanmakta olup minör tükürük bezi yerleşimi nadirdir. Tükürük bezinin neoplastik ve nonneoplastik lezyonlarında psammom cismi varlığı nadirdir. Burada maksiller sinüs yerleşimli, psammom cisimlerinden zengin, AHK olgusu ayırıcı tanıları ile birlikte sunulmaktadır. 59 yaşında erkek hasta bir yıldır devam eden burun tıkanıklığı şikayeti ile hastanemize başvurdu. Hastanın radyolojik görüntülemelerinde maksiller sinüsde, komşu kemik yapılarda ekspansiyona neden olan kitlesel bir lezyon görüldü. Maksillektomi materyalinde makroskopik olarak 6 cm çapındaki tümör izlendi. Tümörden hazırlanan kesitlerde, arada psammom cismi özelliğinde mikrokalsifikasyonlar içeren, asinüs benzeri yapılar izlendi. Tümör hücreleri bazofilik granuler sitoplazmalı, yuvarlak oval nukleuslu idi. Tümör hücreleri PAS ve dPAS ile sitoplazmik granuler tarzda boyandı. Olgu psammom cisimlerinden zengin AHK olarak raporlandı.

Anahtar Kelimeler:

asinik hücreli karsinom, maksilla, psammom cismi

Psammoma Body–Rich Acinic Cell Carcinoma of Maxillary Sinus

Acinic cell carcinoma (ACC) is a rarely seen, slowly growing, low-grade malignant neoplasia of the salivary gland. ACC is most frequently detected in the parotid gland, rarely it is localized in a minor salivary gland. Rarely psammoma bodies are seen in neoplasic, and nonneoplasic lesions of the salivary gland. Herein a case with psammoma body-rich ACC is presented together with its differential diagnosis. A 59-year-old male patient consulted our hospital with complaint of stuffy nose persisting for a year. His radiological examination revealed the presence of a mass lesion in the maxillary sinus which expanded neighbouring bony structures. Macroscopically a tumoral mass with a diameter of 6 cm was observed in maxillectomy specimen in sections prepared from the tumor, acini-like structures containing microcalcifications were observed. Tumor cells had basophilic granular cytoplasm, and round or oval shaped nuclei. Tumor cells stained with PAS and dPAS demonstrated cytoplasmic granules. The case was reported as “psammoma body-rich ACC”.

Keywords:

Acinic cell carcinoma, maxilla, psammoma body,

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