Özlem Yalçın TÖK, LEVENT TÖK, FATMA AKBAŞ KOCAOĞLU, Züleyha YALNIZ, Firdevs ÖRNEK

Sistemik Hodgkin hastalığında iki tarafı lakrimal bez tutulumu

Lakrimal gland tümörlerinin %5’i lenfoid dokudan köken alır. Hodgkin Hastalığının lenfositten zengin tipinde lakri- mal gland tutulumu ise oldukça nadir bir durumdur. Kliniğimiz okuloplasti birimine başvuran, 48 yaşındaki kadın hastanın şikayeti her iki göz kapağında şişlik idi. Muayenede kapaklar çevrildiğinde bilateral lakrimal glan- da uyan bölgede kitle görüldü. Orbita manyetik rezonans görüntülemesinde bilateral bulbus okuli süperolateralin- de, lakrimal bezi tutan, sınırları belirgin, komşu yapıla- ra invazyon göstermeyen, yumuşak doku kitlesi izlendi. Sistemik taramada abdominal, servikal, inguinal, aksiller bölgelerde lenfadenopatilere rastlandı. Lakrimal gland ve aksiller lenf nodu biyopsileri yapıldı. Histopatolojik tanı lenfositten zengin Hodgkin Hastalığı olarak rapor edildi. Hastaya dört kür kemoterapi verildi. Tedavi sonrasında klinik görünüm ve tomografk incelemede bulguların ge- rilediği saptandı.

Involvement of bilateral lacrimal gland in systemic Hodgkin disease

Five percent (5%) of lacrimal gland tumors are originated from lymphoid tissue. In one type of Hodgkin disease which is abounding in lymphocytes, involvement of lacri- mal gland is a rather rare entity. A 48 – year old woman who had swollen both eyelids, applied to department of oculoplasty in our clinic. At in- spection, when eyelids were rotated, a mass was seen at the region which fts to bilateral lacrimal gland area. Magnetic resonance imaging of the orbita showed a well- demarcated soft tissue mass without invade adjacent structure in the supero-lateral aspect of the bilateral orbit, occupying lacrimal gland. Lymphadenopathies in abdomi- nal, cervical, inguinal, axillary regions have been found in systemic scanning. Biopsy of lacrimal gland and axillary lymphadenopahty were performed and histopathological examination revealed the diagnosis as Hodgkin disease abounding in lymphocytes. The patient was underwent four cure chemotherapy. Clinical and tomographic fnd- ings were found to be regressed after treatment.

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