Hasan KIZILTOPRAK, Mustafa KOÇ, Kemal TEKİN, Merve İNANÇ, Erdal KURNAZ, Zehra AYCAN, Pelin YILMAZBAŞ

Sıkı Glisemik Kontrolü olan Tip 1 Diabetes Mellituslu Çocuklarda Yüksek Sıralı Korneal Aberrasyonların Değerlendirilmesi

Amaç: Kan glukoz seviyesi sıkı kontrol altında olan Tip 1 Diabetes Mellituslu (DM) çocuklarda yüksek sıralı korneal aberrasyonların benzer yaş ve cinsiyetteki sağlıklı çocuklarla karşılaştırılması. Yöntemler: Tip 1 DM'li çocukların (DM grubu) ve benzer yaştaki sağlıklı olguların (kontrol grubu) tam oftalmolojik muayenesi yapıldıktan sonra yüksek sıralı korneal aberrasyonları [koma, trefoil, sferik aberasyon, yüksek sıralı root mean square (YS-RMS), toplam RMS] Pentacam HR (Oculus Optikgeräte GmbH, Wetzlar, Germany) ile ölçüldü. Bulgular: DM grubunda 52 hasta (29 erkek, 23 kız) kontrol grubunda 39 (20 erkek, 19 kız) gönüllü bulunmaktaydı. DM grubunda ortalama preprandial kan glukoz değeri 86.4 ± 8.2 mg/dl ve ortalama HbA1c değeri %5.2±0.75 olarak saptandı. DM grubunda yaş ortalaması 12,64±3,75 yıl iken kontrol grubunda 11,94±4,09 yıl idi. İki grup arasında yaş ve cinsiyet açısından istatistiksel olarak anlamlı farklılık yoktu (p=0.745, p=0.364 sırasıyla). Grupların yüksek sıralı korneal aberasyon değerleri [koma, trefoil, sferik aberasyon, yüksek sıralı root mean square (YS-RMS), toplam RMS] karşılaştırıldığında gruplar arasında anlamlı farklılık saptanmadı (p=0,415, p=0,690, p=0,642,p=0,0840, p=0,647, her biri için). Sonuç: Kan glukoz seviyesi iyi kontrol edilen çocuklarda korneanın yüksek sıralı aberasyonları değişmemektedir.

Evaluation of High-Order Corneal Aberrations in Children with Well Controlled Type 1 Diabetes Mellitus

Purpose: To compare the higher-order corneal aberrations of Type 1 Diabetes Mellitus (DM) children who have well controlled glucose level with healthy children of similar age and gender. Methods: After performing a complete ophthalmological examination of children with Type 1 DM (DM group) and similar age-matched healthy controls (Control group), higher order corneal aberration values [coma, trefoil, spherical aberration, higher order root mean square (RMS), total RMS] were measured by Pentacam HR (Oculus Optikgeräte GmbH, Wetzlar, Germany). Results: There were 52 patients (29 males, 23 females) in the DM group and 39 (20 males, 19 females) volunteers in the control group. In the DM group, the mean preprandial blood glucose level was 86.4 ± 8.2 mg/dl and the mean HbA1c value was 5.2 ± 0.75%. The mean age of the DM group was 12,64 ± 3,75 years while it was 11,94 ± 4,09 years in the control group. There was no statistically significant difference in age and gender between the two groups (p = 0.745, p = 0.364 respectively). No statistically significant differences were found between the groups according to higher order corneal aberrations [coma, trefoil, spherical aberration, high order root mean square (RMS), total RMS] (p=0,415, p=0,690, p=0,642,p=0,0840, p=0,647, for each one) Conclusion: Higher order aberrations of the cornea do not change in children whose blood glucose levels are well controlled.

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