SADULLAH GİRGİN, Ömer USLUKAYA, Edip Erdal YILMAZ, Uğur FIRAT, Hatice GÜMÜŞ, Murat KAPAN, Metehan GÜMÜŞ

Granulomatous mastitis: A retrospective review of 49 patients

Amaç: İdiopatik granulomatöz mastit, nadir görülen, be- nign, kronik infamatuar bir hastalık olup meme kanserini taklit eder. Bu çalışmada idiopatik mastitli 49 hastanın te- davisini ve kliniğini sunmayı amaçladık. Yöntemler: Hastane otomasyon sisteminde 2007-2012 yılları arasında histolojik olarak granulomatöz tanısı ko- nulmuş hastalar incelendi. Hastalara ait klinik bulgular, demografik veriler ve tedavi yöntemleri kaydedildi. Bulgular: Ortalama yaş 37.71±7.1 idi. Tedavi gruplar arasında etiyolojik ve demografik açıdan istatistiksel fark yoktu. Nüks oranları grup 1, grup 2 ve grup 3te sırasıyla %8,3, %14,8 %20 olup, gruplar arasında istatistiksel anlamlı farklılık yoktu. Sonuç: Steroid ve cerrahi tedavinin idiopatik granulomatöz mastitli hastalarda uygulanabileceğini, steroid tedavisinin ilk basamak tedavi olması gerektiği kanaatindeyiz. Bununla birlikte tedavi algoritması belirlenebilmesi için prospektif, randomize klinik çalışmalara ihtiyaç vardır.

Granülamatöz mastit: 49 hastanın retrospektif incelenmesi

Objective: Idiopathic granulomatous mastitis, a rare, benign, chronic infammatory condition of the breast, which usually mimics breast carcinoma. In this study, we report on the management of 49 cases of idiopathic granulomatous mastitis and their clinical presentation. Methods: The breast and anatomical databases of one center were reviewed from 2007 to 2012 to identify patients with histological diagnosis of idiopathic granulomatous mastitis. Clinical and demographic characteristics were retrieved and treatment modalities were were recorded. Results: The mean patient age was 37.71±7.1 years. There were no differences between the management groups about etiological and demographic factors. The rate of recurrence in group 1, group 2, and group 3 was 8.3%, 14.8% and 20%, respectively; there were no statistically signifcant difference among the groups. Conclusion: Steroids and surgical methods codifed in idiopathic granulomatous mastitis may be preferred. We recommend steroid therapy as frst-line treatment. However, prospective, randomized clinical trials are needed to determine the treatment algorithm.

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