Effects of Intragastric Balloon on Body Mass Index, Lipid Profile and Blood Glucose Regulation: A Prospective Study

Amaç: Obezite giderek artan bir halk sağlığı ve sosyoe- konomik sorun olmaya devam etmektedir. Sağlıklı bes- lenme ve fiziksel aktivite de dâhil olmak üzere yaşam tar- zı değişiklikleri başarılı kilo kaybı için ilk basamak tedavi şekli olarak kabul görülmektedir. Gastrik balon kilo kaybı için etkili, geri dönüşümlü ve cerrahi olmayan bir yöntem- dir. Çalışmanın amacı, obez hastalarda intragastrik balo- nun kilo kaybı, lipit profili ve kan şekeri düzenlenmesine etkilerini araştırmaktır. Yöntemler: Bu çalışmada hastaların 35,2 ± 9,6 yaş orta- laması ile 75 ardışık mide balonu hastası (55 Bayan, 20 Erkek) çalışmaya dâhil edildi. Çalışma prospektif olarak planlandı ve hava-dolu mide balonu kontrolleri ayaktan poliklinikte yapıldı. Bu çalışmada, hastaların uygulama öncesi vücut kitle indeksi, HbA1c ve lipid profilleri gibi pe- riferik kan parametreleri, kaydedilerek müdahale sonrası değerleri ile karşılaştırıldı. Bulgular: Mide balonu uygulaması için medyan müdaha- le süresi 13 dakika (8-19) idi. Medyan 186 gün (180-211) izlem süresinden sonra, BMI, önemli ölçüde 41,6 ± 6,7 ‘den 34,9 ± 6,4‘e azalma tespit edildi (p

İntragastrik Balonun Vücut Kitle İndeksi, Lipit Profili ve Kan Şekeri Regülasyonu Üzerine Etkileri: Prospektif Çalışma

Objective: Obesity remains an increasing public health and socioeconomic problem. Life style changes including healthy diet and physical activity are the first-line therapy for successful weight loss. The intragastric balloon has been considered as an effective and reversible, non-sur- gical method for weight loss. In this study, we aimed to investigate the effects of Intragastric balloon on weight loss, lipid profiles and blood glucose regulation in obese patients Methods: 75 consecutive Intragastric balloon patients (55 Female, 20 Male) with a mean age of 35.2±9.6 years were included in this study. The study was conducted prospectively and an air-filled intragastric balloon was introduced in ambulatory settings. In this study, patients’ pre-intervention body mass index, peripheral blood pa- rameters such as HbA1c, lipid profiles were recorded and compared with post-intervention values. Results: The median intervention time for intragastric balloon application was 13 min (8-19). After follow-up period of median 186 days (180-211), BMI was reduced significantly, 41.6±6.7 vs. 34.9±6.4 kg/m2 (p<0.001). The median excess weight loss was found to be 33.2% (14- 81.1). There is no statistically significant difference be- tween pre-intervention and post-intervention valuables in terms of low-density lipoprotein, high-density lipoprotein, cholesterol and triglycerides levels (p>0.05). On the other hand, only pre and post-intervention HbA1c level was to be statistically significant (p=0.001) Conclusion: There was significant change in BMI and HbA1c level with the intervention of intragastric balloon after follow-up period. For long-term benefit of balloon, further studies are needed.

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Dicle Tıp Dergisi-Cover
  • ISSN: 1300-2945
  • Yayın Aralığı: 4
  • Başlangıç: 1963
  • Yayıncı: Cahfer GÜLOĞLU
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