Fatma PAKSOY, TURGAY ULAŞ, Cemal BES, MEHMET SİNAN DAL, Fatih BORLU

Corrected Qt interval in patients with metabolic syndrome

Metabolik sendrom artmış kardiyovasküler mortalite ve morbidite ile ilişkili olabilir. Fakat metabolik sendromun QT sürelerinin uzamasına neden olduğu halen belirsizdir. Bu çalışmanın amacı metabolik sendromla birlikte bulunan uzamış QT süresinin sıklığını araştırmak ve varsa aralarındaki ilişkiyi göstermektir. Bu amaçla geniş bir hasta grubunda metabolik sendromun QT uzaması ile ilişkisini araştırmayı amaçladık. Gereç ve yöntem: Çalışmaya 1009 hasta dahil edildi. Metabolik sendrom IDF kriterlerine göre tanımlandı ve QT süresi Bazett formülü kullanılarak hesaplandı. QT≤0,44 sn normal olarak kabul edildi. Bulgular: Çalışmaya alınan 1009 olgunun 278’i erkek, 731’i kadındı. Erkeklerin Bazett formülüne göre düzeltilmiş ortalama QT sureleri 0,448±0,040 sn, kadınların ise 0,449±0 ,050 sn idi. Hem erkek hem de kadın hastalarda QTc suresi normale göre anlamlı yüksek bulundu (p< 0,01). Sonuç: Metabolik sendrom uzamış QT süresiyle ilişkili bulundu. Çalışmamızda elde ettiğimiz bulgular metabolik sendrom hastalarında QT süresinin artmış olduğunu desteklemektedir.

Metabolik sendromlu hastalarda düzeltilmiş Qt süresi

Metabolic syndrome may be associated with increased cardiovascular mortality and morbidity. However, prolongation of QT intervals due to metabolic syndrome is still unclear. The purpose of this study was to investigate the incidence prolonged QT intervals in patients with metabolic syndrome and also demonstrate the relationship between them. Therefore, we aimed to investigate the relationship between metabolic syndrome and the QT prolongation in a large patient group. Materials and methods: A total of 1009 individuals were enrolled in this study. Metabolic syndrome was defined according to the IDF criteria and the QTc intervals were measured by using Bazett Formula. QT ≤ 0.44 second was accepted as normal. Results: Totally, 278 male and 731 female individuals of 1009 cases were enrolled in this study. The average duration of corrected QT of men according to the Bazzett formula were found as 0,448±0,04 second and QT interval of women were 0,449±0,05 second. QT intervals of both women and men with metabolic syndrome were significantly higher than normal limits of QT interval (p<0,01). Conclusion: Metabolic syndrome found as associated with a prolonged QTc. Results of our study suggest that QTc interval length was increased in patients with metabolic syndrome.

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