BRUGADA SENDROMU/ BRUGADA PATERNİ VE ATEŞ ARASINDAKİ İLİŞKİ

Brugada sendromu otozomal dominant olan kalıtsal bir kardiyak sodyum kanalopatisidir. Yapısal olarak normal bir kalbe sahip olmalarına rağmen, Brugada sendromlu kişilerde ani kardiyak ölüm riski yüksektir. Tanı için kullanılan elektrokardiyogram (EKG) paterni spontan olarak veya sodyum kanal bloker testi sırasında görülebilir. Büyük nüfus kohortlarından elde edilen son bulgulara rağmen, etkilenen hastalar arasında risk sınıflandırması hala zordur. Yakın zamanda Brugada sendromunda ani kardiyak ölüm riskini sınıflandırmak için çok sayıda risk faktörü önerilmiştir. Belirgin bir çukur veya eyer şeklindeki ST segment yükselmesinin ardından V1-V3'te T dalgası değişiklikleri olarak tanımlanabilir ve başka bir neden yokluğunda Brugada paterni olarak adlandırılır. Brugada sendromu, bazen ateş ve çeşitli enfeksiyonlarla tetiklenebilir. Bu derlemede amacımız Brugada sendromu, ateş ve enfeksiyonlarla ilgili literatürü incelemekti.

THE CORRELATION BETWEEN BRUGADA SYNDROME/ BRUGADA PATTERN AND FEVER

Brugada syndrome is a hereditary cardiac sodium channelopathy that is autosomal dominant. Despite having a structurally normal heart, people with Brugada syndrome have an increased risk of sudden cardiac death. The electrocardiogram (ECG) pattern used for diagnosis can be seen either spontaneously or during a sodium channel blocker test. Despite recent findings from sizable population cohorts, risk stratification among affected patients is still difficult. Numerous risk factors for stratifying the risk of sudden cardiac death in Brugada syndrome have recently been proposed. The Brugada pattern is defined as a significant coved or saddle-shaped ST-segment elevation followed by T wave shifts in V1–V3 and without any other obvious explanation. Brugada syndrome or Brugada pattern can be occasionally precipitated by fever and several infections. In this review, our goal was to examine the literature in relation to Brugada syndrome/ Brugada pattern and fever.

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