Tayup ŞİMŞEK, Tayfun TOPTAŞ, Hülya AYDIN AYIK

Servikal intraepitelyal neoplazi grade 1: Tedavi edilmemiş kadınlarda rekürrens, persistans ve progresyon

Amaç: Düşük dereceli servikal intraepitelyal neoplazi (CIN) oldukça yaygın bir bozukluktur. Tedavi edilmemiş kadınlarda rekürrens, persistans ve progresyonu içeren hastalığın seyri iyi bilinmemektedir. Bu çalışmanın amacı 3 yıllık takip sürecinde CIN1in doğal gidişatını belirlemektir. Yöntem: Bu retrospektif çalışma, 2009 ve 2015 yılları arasında, üçüncü basamak bakım merkezimizdeki jinekolojik onkoloji bölümünde CIN1 tanısı almış 545 hastanın tıbbi verilerini içermektedir. İlk servikal smear sonuçları; 1., 2. ve 3. yıl takiplerdeki sonuçlarla karşılaştırıldı. Bulgular: İlk smear sonuçları takip örneklerle karşılaştırıldığında 1., 2. ve 3. yıllara kıyasla anlamlı iyileşme göstermiştir (p

Cervical squamous intraepithelial neoplasia grade 1: Recurrence, persistence, and progression in untreated women

Objective: Low grade cervical intraepithelial neoplasia (CIN) is a relatively common disorder. The course of disease including recurrence, persistence, and progression in untreated women is not well-known. The aim of the present study was to determine the natural history of CIN 1 during a follow-up period of 3 years. Method: This retrospective study involved data extracted from the medical files of 545 patients diagnosed with CIN 1 between 2009 and 2015 in the obstetrics and gynecology department of a tertiary care center. Initial cervical smear results were compared to those on the follow-up visits at 1st, 2nd and 3rd years. Results: Comparison of initial smear results with follow-up samples yielded significant improvements on 1st, 2nd, and 3rdyears (p

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