Zekiye HASBEK, Hulusi EĞİLMEZ, Taner ERSELCAN, Cesur GÜMÜŞ, Serdar GÜL

Pulmonary alveolar microlithiasis: Quantitative approach by bone scintigraphy

Pulmoner alveolar mikrolitiyazis (PAM) etiyoloji ve patogenezi bilinmeyen nadir idiopatik bir hastalıktır. Histopatolojik olarak her iki akciğer parankiminde yaygın intra-alveolar kalsiyum ve fosfat çökmesi ile karakterizedir. Pulmoner kalsifikasyon ve ossifkasyonun non-invaziv tanısı direkt akciğer grafisi, bilgisayarlı tomografi gibi görüntüleme tekniklerini gerektirirken, kemik sintigrafisi de kantitatif analiz ile hastalığın düzeyi hakkında bilgi vererek rol alabilir. Bu raporda, bir PAM hastasının bir birini takip eden kemik sintigrafilerinde rölatif dansite analizi ile akciğerlerdeki kalsifiye odakların kantitatif olarak değerlendirildiği bir yöntem sunuldu.

Pulmoner alveolar mikrolitiyazis: Kemik sintigrafisi ile kantitatif yaklaşım

Pulmonary alveolar microlithiasis (PAM) is a rare idiopathic disease of unknown etiology and pathogenesis. PAM is characterized histopathologically by extensive intra-alveolar calcium and phosphate deposition throughout both lung parenchymas. None-invasive diagnosis of pulmonary calcification and ossification requires various imaging techniques, including chest radiography and computed tomography, while bone scintigraphy may play a role in the disease staging by quantitative analysis. In this report, we presented a quantitative assessment technique for calcified foci in lungs by means of relative density analysis in successive bone scintigraphies of a patient with PAM.

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