Serife GÜL ÖZ, Zhaleh EMARATPARDAZ, Lale ÖZIŞIK, Nursel BASARAN ÇALIK, Mine TANRIOVER DURUSU

Overutilization of proton pump inhibitors and H2 receptor antagonists in hospitalized medical patients

Amaç: Hastanede yatmakta olan hastalarda proton pompa inhibitörleri (PPİ) ve histamine-2 reseptör antagonistlerinin (H2RA) kullanılma sıklığı ve tercihine ilişkin veriler yoktur. İç Hastalıkları servislerinde sık olarak kullanılan PPİ ve H2RA kullanım sıklıklarını belirlemektir. Yöntem: Retrospektif olarak, 1 Ocak ve 31 Aralık 2010 tarihleri arasında bir üçüncü basamak üniversite hastanesinin İç Hastalıkları servislerinde ve yoğun bakım ünitelerinde (YBÜ) yatırılan hastaların tıbbi kayıtları incelendi; herhangi bir PPİ veya H2RA kullanımı olan olguların dörtte biri rastgele olacak şekilde seçildi. Bulgular: 2010 yılında, İç Hastalıkları servislerinde yatırılan toplam 4730 hastanın yarısı bir H2RA veya PPİ kullanmıştı. Bunların içinden 556 (%25.5) olgu incelendi. Olguların büyük çoğunluğu (%76) PPİ kullanmaktaydı. Servislerde, PPİ olguların %90.3'ünde kullanılırken, YBÜ'de olguların %74.8'i H2RA kullanmaktaydı (p

Proton pompa inhibitörleri ve H2 reseptör antagonistlerinin iç hastalıkları servislerinde yatmakta olan hastalarda aşırı kullanımı

Objective: The aim of the study was to determine the frequency of the use of proton pump inhibitors (PPI) and histamine-2 receptor antagonists (H2RA), which are widely used drugs, in the medical wards. Method: We retrospectively retrieved medical records of the patients who were hospitalized between January 1st and December 31th, 2010 in a tertiary care university hospital internal medicine wards and medical intensive care unit (MICU); one fourth of the cases who used a H2RA or a PPI drugs were randomly selected for the study. Results: In 2010, half of 4730 patients who admitted to internal medicine wards was ordered a H2RA or a PPI. Of these, 556 patients (25.5%) were evaluated. Majority of the patient (76%) were on PPI. While 90.3% of the patients used a PPI in wards, 74.8% of the patients used a H2RA in the MICU (p

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