Mohamad Javad SHAFEIE, Seyed Mohsen SALEH KOOTAHI

Therapeutic Radiopharmaceuticals with Alpha Emitters, Properties and Microdosimetry

Abstract. Having useful properties in therapeutic radiopharmaceuticals, Radionuclides with alpha emitters plays a significant role in curing cancers. Some properties like short range and deposited energy in unit length of pathway cause to enhance the effect of alpha particle on destroying the DNA of cancer cells. Therefore, recognizing this capacity involves more investigations over the biological effect of these particles on human body. Properties of alpha emitters led to exert profound differences between this field and other fields of nuclear medicine. In order to understand the effect of alpha particles and optimizing the trend of corresponding research, Microdosimetry is considered as an influential tool.

Keywords:

Alpha emitters Radioimmunotherapy, Microdosimetry,

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