Kikuchi Fujimoto hastalığında steroid kullanım endikasyonları: bir olgu sunumu
Kİkuchi Fujimoto Hastalığı (KFH), etiyolojisi tam olarak bilinmeyen, genellikle selim seyreden ve kendini sınırlayan bir hastalıktır. KFH için bir tedavi kılavuzu bulunmamaktadır; tedavi önerileri klinik deneyime dayanır ve genel yaklaşım destek tedavisi şeklindedir. Ancak hastalık bazen ciddi bir seyir izler. Ağır seyreden, dirençli semptomları olan ve tekrarlayan hastalık için daha net ve etkili tedavi seçeneklerine ihtiyaç vardır. Biz de yazımızda, sistemik steroide yanıt veren bir olgumuz aracılığıyla, KFH' da steroid kullanım endikasyonlarını vurgulamak istedik.
Highlighting steroid indications for Kikuchi Fujimoto disease: a case report
Kikuchi Fujimoto disease (KFD) is a rare, generally benign and self limited condition with an unknown etiology. There isn’t a guideline for treatment of KFD, recommendations for treatment are based on clinical experience and management is typically supportive. However, sometimes more ominous course of the disease may be experienced. Thus, for the patients with severe disease, refractory symptoms and recurrences, more definite and efficient treatment options are required. Here, we aimed to emphasize the indications of steroid treatment via a case of KFD resolved after systemic steroids.
___
- Referans1) Y J Jang, K H Park, H J Seok. Management of Kikuchi's disease using glucocorticoid. J Laryngol Otol. 2000;114:709-11.
- Referans2) D Y Lin, M S Villegas, P L Tan, S Wang, L P Shek. Severe Kikuchi's disease responsive to immune modulation. Singapore Med J. 2010;51:18-21.
- Referans3) S Yalcin, S K Toprak, B Erismis, O Altundag, H Ozdemir, N Topcuoglu. Management of Kikuchi-Fujimoto disease using glucocorticoid: a case report. Case Reports in Medicine. 2011;230840.
- Referans4) D Deaver, P Horna, H Cualing, L Sokol. Pathogenesis, diagnosis, and management of Kikuchi-Fujimoto disease. Cancer Control. 2014;21:313-321.
- Referans5) C Costantino, P Stenzel. Kikuchi-Fujimoto disease with lymph node, spleen, and liver involvement: Report of a fatal adult case with hemophagocytic lymphohistiocytosis. Human Pathology: Case Reports. 2016;5:1-5.
- Referans6) S Y Kwon, T K Kim, Y S Kim, K Y Lee, N J Lee, H Y Seol. CT findings in Kikuchi disease: Analysis of 96 cases. AJNR Am J Neuroradiol. 2004;25:1099-102
- Referans7) K Yasukawa, T Matsumura, K C Sato-Matsumura, T Takahashi, Y Fujioka, H Kobayashi et al. Kikuchi's disease and the skin: case report and review of the literature. Br J Dermatol. 2001;144:885-9.
- Referans8) Masab M, Surmachevska N, Farooq H. Kikuchi Disease. Continuing Education Activity. https://www.ncbi.nlm.nih.gov/books/NBK430830
- Referans9) Bosch X, Guilabert A, Miquel R, Campo E. Enigmatic Kikuchi-Fujimoto Disease- A Comprehensive Review. Am J Clin Pathol. 2004;122:141-52.
- Referans10) Lee EJ, Lee HS, Park JE, Hwang JS. Association Kikuchi disease with Hashimoto thyroiditis: a case report and literature review. Ann Pediatr Endocrinol Metab. 2018;23:99-102.