ALLERGENIC COMPOUNDS IN HONEY BEE PRODUCTS

Öz Allergy can be defined as a strong specific reaction of the human body to exogenous molecules that may occur in the normal environment. Food allergies are individualistic adverse reactions to foods. Food related reactions are individualistic because they affect only a few people in the population: most people can eat the same foods with no reactions. Adverse food reactions can include IgE and non IgE mediated primary immunological sensitivities, food intolerances, a secondary sensitivities. Bee products such as honeybees, honey, royal jelly and pollen are widely consumed as a health supplement. These products are reported in various reports that may cause allergic reactions when consumed. In this study, the allergic effects and allergen components of bee products consumed as food are described. These allergens include high molecular weight proteins in the bee pollen and honey, MRJ1 and MRJ2 in the royal jelly, and 3-methyl-2-butenyl caffeate, phenylethyl caffeate, benzyl caffeate, geranyl caffeate, benzyl alcohol benzyl cinnammate, methyl cinnammate, ferulic acid, tecto chrysin in the propolis

Anahtar Kelimeler:

Allergy, honey, bee pollen, royal jelly, propolis

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1 S. Cochrane, K. Beyer, M. Clausen M. Factors influencing the incidence and prevalence of food allergy. Allergy, 64, (2009) 1246–1255.

2 H.A. Sampson. Food allergy. Journal of Allergy and Clinical Immunology, 111 (2003) 540–547.

3 J.A. Chapman, I.L. Bernstein, R.E. Lee, J. Oppenheimer. Food allergy: a practice parameter. Annals of Allergy, Asthma & Immunology, 96 (3-Suppl 2), (2006) 1-68.

4 M. Turkalj, I. Mrkic. Alergijske reakcije na hranu. Liječ Vjesn, 134, (2012)168–173.

5 S.L. Taylor, S.L. Hefle. Food Allergies and other food sensitivities. A publication of the Institute of Food Technologists’ expert panel on food safety and nutrition. Food Technology, 55(9), (2001) 68-83.

6 L. Bauer, A. Kohlich, R. Hirschwehr, U. Siemann, H. Ebner, O. Scheiner, D. Kraft, C. Ebner. Food allergy to honey: pollen or bee products? Characterization of allergenic proteins in honey by means of immunoblotting. Journal of Allergy and Clinical Immunology, 97(1), (1996) 65-73.

7 N. Fuiano, C. Incorvaia, G.G. Riario-Sforza, G. Casino. Anaphylaxis to honey in pollinosis to mugwort: a case report. European Annals of Allergy and Clinical Immunology, 38(10), (2006) 364-5.

8 A. Hebling, Ch. Peter, E. Berchtold, S. Bogdanov, U. Müller. Allergy to honey: relation to pollen and honeybee allergy. Journal of Allergy and Clinical Immunology, 97(1), (1996) 65-73.

9 M.F. Martin-Munoz, B. Bortolome, M. Caminoa, I. Bobolea, M.C. Ara, S. Quirce. Bee pollen: a dangerous food for allergic children. identification of responsible allergens. Allergologia et Immunopathologia (Madr.), 38(5), (2010) 263-265.

10 S.H. Cohen, J.W. Yunginger, N. Rosenberg, J.N. Fink. Acute allergic reaction after composite pollen ingestion. Journal of Allergy and Clinical Immunology, 64, (1979) 270–274.

11 J. Bousquet, J. Campos, F.B. Michel. Food intolerance to honey. Allergy, 39, (1984) 73-75.

12 H.K. Güngör, Akyol A. Pathogenesis of chronic urticaria. Turkish Journal of Dermatology, 4, (2014) 223-6.

13 M.I. Fogg, E. Ruchelli, J.M. Spergel. Pollen and eosinophilic esophagitis. Journal of Allergy and Clinical Immunology, 112(4), (2003), 796-7.

14 M. Rosmillah, M. Shahnaz, G. Patel, J. Lock, D. Rahman, A. Masita, A. Noormalin. Characterization of major allergens of royal jelly Apis mellifera. Tropical Biomedicine, 25(3), (2008) 243-251.

15 C. Lombardi, G.E. Senna, B. Gatti, M. Feligioni, G. Riva, P. Bonadonna, A.R. Dama, G.W. Canonica, G. Passalacqua. Allergic reactions to honey and royal jelly and their relationship with sensitization to compositae. Allergologia et Immunopathologia (Madr.), 26(6), (1998) 288-290.

16 S.E. Walgrave, E.M. Warshaw, L.A. Glesne. Allergic contact dermatitis from propolis. Dermatitis, 16(4), (2005) 209-215.

17 C. Gardana, P. Simonetti. Evaluation of allergens in propolis by ultra- performance liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 25 (2011) 1675–82.