CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF SEVEN DIFFERENT GRAPE EXTRACTS

Öz Grape extracts have strong antioxidant potential which can make them promising anticancer and food-supplement. However, one of the main obstacles is that there is not enough data revealing content of the grape extracts. Another important issue is that grape extracts are mostly obtained in methanol and ethanol solvent, which can limit their effective usage. Therefore, in this study, extracts of seven different grape species of white and red grape (which were collected from Kırşehir-Toklumen) were collected using 70:30 water:ethanol, which underwent GC-EI-MS characterization. GC-MS based characterization revealed that the species had key content differences and similarities, which can trigger further research to quantify the content to reveal what exactly brought the differences in the obtained antioxidant potential of the grape species

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P. Suppakul, J. Miltz, K. Sonneveld and S.W. Bigger, Antimicrobial properties of basil and its possible application in food packaging. Journal of Agricultural and Food Chemistry, 51, (2003) 3197–3207.

R. Mickiene, B. Bakutis and V. Baliukoniene, Antimicrobial activity of two essential oils. Annals of Agricultural and Environmental Medicine, 18 (1), (2011) 139-44.

M.F. Balandrin, J.A. Klocke, E.S. Wurtele, W.H. Bollinger, Natural plant chemicals: sources of industrial and medicinal materials. Science, 228, (1985) 1154–1160.

M.J. Tuorkey, Cancer therapy with phytochemicals: present and future perspectives. Biomedical and Environmental Sciences, 28, (2015) 808–819.

F. Conforti, G. Ioele, G.A. Statti, et al Antiproliferative activity against human tumor cell lines and toxicity test on Mediterranean dietary plants. Food and Chemical Toxicology, 46, (2008) 3325–3332.

B. Dzhambazov, S. Daskalova, A. Monteva, and N. Popov, In vitro screening for antitumour activity of Clinopodium vulgare L.(Lamiaceae) extracts. Biological and Pharmaceutical Bulletin, 25, (2002) 499–504.

S. Bail, G. Stuebiger, S. Krist, H.Unterweger, and G.Buchbauer, Characterisation of various grape seed oils by volatile compounds, triacylglycerol composition, total phenols and antioxidant capacity. Food Chemistry, 108, (2008) 1122–1132.

C. Pérez, M.L.R. del Castillo, C. Gil, G.P. Blanch, and G. Flores, Supercritical fluid extraction of grape seeds: extract chemical composition, antioxidant activity and inhibition of nitrite production in LPS-stimulated Raw 264.7 cells. Food & Function, 6, (2015) 2607–2613.

H. Atmaca, E. Bozkurt, M. Cittan, and H. Dilek Tepe, Effects of Galium aparine extract on the cell viability, cell cycle and cell death in breast cancer cell lines. Journal of Ethnopharmacology,186, (2016) 305–310.

O.P. Sharma and T.K. Bhat, DPPH antioxidant assay revisited. Food Chemistry, 113, (2009) 1202–1205.

P. Iacopini, M. Baldi, P. Storchi and L. Sebastiani, Catechin, epicatechin, quercetin, rutin and resveratrol in red grape: Content, in vitro antioxidant activity and interactions. Journal of Food Composition and Analysis, 21, (2008) 589–598.

V.M. Burin, N.E. Ferreira-Lima, C.P. Panceri and M.T. Bordignon-Luiz Bioactive compounds and antioxidant activity of Vitis vinifera and Vitis labrusca grapes: Evaluation of different extraction methods. Microchemical Journal,114, (2014) 155–163.

E.A. Hayouni, M. Abedrabba, M. Bouix and M. Hamdi The effects of solvents and extraction method on the phenolic contents and biological activities in vitro of Tunisian Quercus coccifera L. and Juniperus phoenicea L. fruit extracts. Food Chemistry, 105, (2007) 1126–1134 .

N.S. Kelley, N.E. Hubbard and K.L. Erickson, Conjugated linoleic acid isomers and cancer. The Journal of Nutrition, 137, (2007) 2599–2607.