Yakup ERGÜL, Kemal NİŞLİ, Aygün DİNDAR, Ümrah AYDOĞAN, Rukiye Eker ÖMEROĞLU, Türkan ERTUĞRUL

Primer Raynaud Sendromunda Akut Vasküler Komplikasyonlar ve Tedavi

Primer İdyopatik Raynaud sendromu, sıklıkla kızları etkileyen ve kollajen doku hastalıkları gibi diğer sistemik tablolara eşlik etmeyen Raynaud fenomenli hastaları tanımlar. Raynaud fenomeni daha çok distal ekstremiteler- de belirgin olan; kendiliğinden, soğuk veya fiziksel- emosyonel stresle tetiklenen üç fazlı soluklaşma-siyanoz- eritem bir reaksiyondur. Çocuklarda ender olarak görülen bu tablo, sıklıkla geri dönüşlü olmakla birlikte ciddi vaka- larda iskemi ve nekrozlara yol açabilir. Hastalığın idame tedavisinde kalsiyum kanal blokerleri kullanılırken acil tedavide antikoagülan, pentoksifilin, nitroprussit ve prazo- sin kullanılabilir. Özellikle soğuktan korumak ve distal ekstremiteleri sıcak tutmak koruyucu tedavide önemlidir. Bu yazıda akut arteryel iskemi ile gelen primer Raynaud sendromlu iki kız hastada acil tedavi ve koruyucu önlemler tartışılmıştır

Anahtar Kelimeler:

Primer Raynaud sendromu, vasküler komplikasyon, kalsiyum kanal blokerleri

Acute Vascular Complications and Treatment in Primary Raynaud’s Syndrome

Primary Raynaud’s syndrome includes the Raynaud’s phe- nomenon mostly affects girls and is not associated with connective tissue diseases. Raynaud phenomenon descri- bes triphasic color changes of pallor, cyanosis and erythe- ma limited to distal extremities triggered by physical- emotional stres. Although this phenomenon is reversible, progression to necrosis may develop in serious cases. While, Ca-Channel blockers are used for long-term the- rapy, anticoagulant agents, pentoxyphillin, nitroprusside and prazosine can be given for acute treatment. Keeping distal extremities warm and protecting from cold stres are important for prevention. In this study, acute and long-term treatment of acute arterial ischemia in two female patients with primary Raynaud’s syndrome have been presented

Keywords:

Primary Raynaud’s syndrome, vascular complication, Ca-Channel blockers,

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