Ahmet İbrahim BAŞ, Bağdagül AKSU, Ayse AGBAS, Cansu BAŞ, Murat ELEVLİ

Nörojenik Mesaneli Çocuklarda Serum Çinko Düzeyinin Değerlendirilmesi

Amaç: Bu çalışmada, nörojenik mesane tanılı çocuklarda serum çinko düzeyinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Çalışmamıza 1 Ocak 2015-31 Aralık 2018 tarihleri arasında hastanemiz Çocuk Nefrolojisi Polikliniği’ne başvuran 47 nörojenik mesane tanılı hasta ve çocuk polikliniğine rutin kontrol amaçlı başvuran, akut veya kronik herhangi bir hastalığı olmayan 35 sağlıklı çocuk alındı. Çalışmaya dahil edilen bütün çocukların kan sayımı, biyokimyasal parametreleri ve serum çinko düzeyleri hastane bilgi sisteminden alınarak hazırlanmış olan forma not edildi. Bulgular: Çalışmamızda nörojenik mesane tanılı çocuklarda kontrol grubuna göre serum çinko düzeyi daha düşüktü (sırasıyla 71,6±16,5 µg/dl ve 82,5±12,0 µg/dl, p=0,001) ve çinko eksikliği bu gruptaki çocuklarda daha fazlaydı (sırasıyla %51,0 ve %14,3 p=0,001). Çalışma grubunda serum çinko düzeyleri ile hemoglobin, hematokrit, serum kalsiyum ve alkalen fosfataz değerleri arasında anlamlı ve pozitif korelasyon saptandı. Sonuç: Nörojenik mesane tanılı çocukların serum çinko düzeyinin sağlıklı çocuklardan düşük olduğunu saptadık. Bu nedenle nörojenik mesane tanısıyla izlenen çocukların takibi sırasında anemi, vitamin ve mineral eksikliği açısından daha yakından izlenmesi, beslenmelerinin düzenlenmesi, gerekiyorsa vitamin ve mineral desteğinin yapılması gerekmektedir.

Anahtar Kelimeler:

Nörojenik mesane, spina bifida, çinko eksikliği

Evaluating Serum Zinc Levels in Children with Neurogenic Bladder

Objective: The aim of this study is to evaluate serum zinc levels in children with neurogenic bladder. Materials and Methods: The study involves 47 patients with neurogenic bladder who applied to the Pediatric Nephrology Outpatient Clinic of our hospital between January 1, 2015 and December 31, 2018 as well as 35 healthy children with no acute or chronic disease. The blood count, biochemical parameters, and serum zinc levels of all children included in the study were taken from the hospital information system. Results: In our study, serum zinc levels were lower in children with neurogenic bladder compared to the control group (71.6±16.5 µg/dl vs. 82.5±12.0 µg/dl, respectively; p=0.001), and zinc deficiency was higher in the patient group (51% vs. 14.3%, respectively; p=0.001). A significant positive correlation was found in the study group between serum zinc levels and their hemoglobin, hematocrit, serum calcium, and alkaline phosphatase levels. Conclusion: We determined the serum zinc levels in children with neurogenic bladder to be lower than those in healthy children. Therefore, children with neurogenic bladder need to be monitored more closely during their follow-up in terms of anemia, vitamin and mineral deficiencies, and nutrition regulation, and be provided with vitamin and mineral supplements if necessary.

Keywords:

Neurogenous bladder, spina bifida, zinc deficiency,

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